Evidence map›Paper›PMID 9423883›Full record

ArticleInfection and immunity1998

Molecular characterization of an outer membrane protein of Actinobacillus actinomycetemcomitans belonging to the OmpA family.

P A White, S P Nair, M J Kim, M Wilson, B Henderson

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Aggregatibacter actinomycetemcomitans - a tooth killer?Journal of clinical and diagnostic research : JCDR · 2014
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

P A WhiteSchool of Biological Sciences, Macquarie University, Sydney, New South Wales, Australia. pwhite@rna.bio.mq.edu.au
S P Nair
M J Kim
M Wilson
B Henderson
Macquarie University · AUNational Medical Research Center of Dentistry and Maxillofacial Surgery · RUUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The major outer membrane protein (OMP) of Actinobacillus actinomycetemcomitans is an OmpA homolog that demonstrates electrophoretic heat modifiability. The gene encoding this protein was isolated from a genomic library of A. actinomycetemcomitans NCTC 9710 by immunoscreening with serum from a patient with localized juvenile periodontitis. Expression of the cloned gene in Escherichia coli and subsequent Western blot analysis revealed a protein with an approximate molecular mass of 34 kDa. The amino acid sequence predicted from the cloned gene demonstrated that the mature protein had a molecular mass of 34,911 Da and significant identity to members of the OmpA family of proteins. We have named the major OMP of A. actinomycetemcomitans Omp34, and its corresponding gene has been named omp34.

Indexed as

Escherichia coli ProteinsAggregatibacter actinomycetemcomitansAggressive PeriodontitisAmino Acid SequenceBacterial Outer Membrane ProteinsBase SequenceBlotting, WesternCloning, MolecularEscherichia coliGene ExpressionGene LibraryHumansMolecular Sequence DataPlasmidsRestriction MappingSequence AlignmentBacterial Outer Membrane ProteinsEscherichia coli ProteinsOMPA outer membrane proteins

Identifiers

PMID9423883
PMCPMC107906
OpenAlexW2157724641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.