Evidence map›Paper›PMID 9422590›Full record

ArticleJournal of bacteriology1998

All seven comG open reading frames are required for DNA binding during transformation of competent Bacillus subtilis.

Y S Chung, D Dubnau

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 104 citations in OpenAlex.

  1. Article
  2. Metal-independent effects of calprotectin on cocultures ofbioRxiv : the preprint server for biology · 2026
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  6. Evidence ofApplied and environmental microbiology · 2025
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  7. Review
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  12. Review
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  15. Article
  16. Article
  17. Article
  18. The Role of Minor Pilins in Assembly and Function of the Competence Pilus ofFrontiers in cellular and infection microbiology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Y S ChungPublic Health Research Institute, New York, New York 10016, USA.
D Dubnau
Public Health Institute · US

Funding

GENETIC COMPETENCE APPARATUS OF BACILLUS SUBTILLISR01GM043756 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI DUBNAU, DAVID A · 1991 to 2016
$7.2M
NIGMS NIH HHS GM43756NIGMS NIH HHS R01 GM043756
6 · The paper itself

Abstract

The seven proteins encoded by the comG operon of Bacillus subtilis exhibit similarity to gene products required for the assembly of type 4 pili and for the secretion of certain proteins in gram-negative bacteria. Although polar transposon insertions in comG result in the loss of transformability and in the failure of cells grown through the competence regimen to bind DNA, it was not known whether the ComG proteins are all required for competence. We have constructed strains missing each of these proteins individually and found that they are all nontransformable and fail to bind transforming DNA to the cell surface. The implications of these findings are discussed.

Indexed as

Amino Acid SequenceBacillus subtilisBacterial ProteinsDNA, BacterialFimbriae, BacterialGenetic Complementation TestMolecular Sequence DataMutationOpen Reading FramesOperonPhenotypeTransformation, BacterialBacterial ProteinsDNA, Bacterial

Identifiers

PMID9422590
PMCPMC106846
OpenAlexW1622133577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.