ArticleThe American journal of pathology1998
Consistent copy number gain in chromosome 12 in primary diffuse large cell lymphomas of the stomach.
Article in The American journal of pathology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 56 citations in OpenAlex.
- Article
- Prediction of potential cancer-risk regions based on transcriptome data: towards a comprehensive view.PloS one · 2014Article
- Article
- Novel genomic imbalances in B-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics.The American journal of pathology · 2001Article
- Importance of extensive staging in patients with mucosa-associated lymphoid tissue (MALT)-type lymphoma.British journal of cancer · 2000Article
- Clinicopathological features of gastric mucosa associated lymphoid tissue (MALT) lymphomas: high grade transformation and comparison with diffuse large B cell lymphomas without MALT lymphoma features.Journal of clinical pathology · 2000Article
- Characteristic chromosomal imbalances in primary central nervous system lymphomas of the diffuse large B-cell type.Brain pathology (Zurich, Switzerland) · 2000Article
- Expression of cdc2 and cyclin B1 in Helicobacter pylori-associated gastric MALT and MALT lymphoma : relationship to cell death, proliferation, and transformation.The American journal of pathology · 2000Article
- Exclusive detection of the t(11;18)(q21;q21) in extranodal marginal zone B cell lymphomas (MZBL) of MALT type in contrast to other MZBL and extranodal large B cell lymphomas.The American journal of pathology · 1999Article
- Chromosomal imbalances in primary lymphomas of the central nervous system.The American journal of pathology · 1999Article
- Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis: relationship to disease stage, tumor size, and cirrhosis.The American journal of pathology · 1999Article
- Trisomy 3 is not a common feature in malignant lymphomas of mucosa-associated lymphoid tissue type.The American journal of pathology · 1998Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fifteen cases of high grade primary gastric non-Hodgkin's lymphomas were studied using comparative genomic hybridization (CGH) and/or fluorescence in situ hybridization (FISH) techniques. A total of 10 cases of diffuse large cell lymphoma (DLCL) with no histologically identifiable or previous history of low grade mucosa-associated lymphoid tissue (MALT) lymphoma components were examined, four by CGH and validated by FISH, and the remaining six by FISH alone. All 10 tumors showed gains in chromosome 12. Other recurring CGH findings in DLCL included copy number gains of 1q and deletions of 6q. Five cases of high grade tumors with low grade MALT components (HGM) were also examined, three by CGH and validated by FISH and two by FISH only. Only one in five HGM showed gains of chromosome 12. Other recurring CGH findings in HGM included +7q and +11q. We conclude that high grade gastric lymphomas of DLCL type were associated with gains in chromosome 12. The change was much less frequent (P < 0.01) in the HGM type, which had a percentage similar to that observed in previously reported cytogenetics/FISH studies on low grade MALT lymphomas. Our findings suggested that many DLCL were not derived from transformation of low grade MALT lymphomas.
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9422517PMC1858110W160621721What OpenQuestion holds
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