ReviewDrugs & aging1997
Age-associated memory impairment. Normal aging or warning of dementia?
Review in Drugs & aging, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- The Impact of Adverse Childhood Experiences on Cognitive Control Across the Lifespan: A Systematic Review and Meta-analysis of Prospective Studies.Trauma, violence & abuse · 2025Pooled it
- Semantic item-level metrics relate to future memory decline beyond existing cognitive tests in older adults without dementia.Psychology and aging · 2023Article
- Towards bridging the grey digital divide: changes in internet access and its predictors from 2002 to 2014 in Germany.European journal of ageing · 2020Article
- Detection of Rater Errors on Cognitive Instruments in a Clinical Trial Setting.The journal of prevention of Alzheimer's disease · 2018Article
- Lest we forget: comparing retrospective and prospective assessments of adverse childhood experiences in the prediction of adult health.Journal of child psychology and psychiatry, and allied disciplines · 2016Article
- What do temporal lobe epilepsy and progressive mild cognitive impairment have in common?Frontiers in systems neuroscience · 2014Review
- Mild cognitive impairment: conceptual, assessment, ethical, and social issues.Clinical interventions in aging · 2008Review
- Hippocampal size and memory function in the ninth and tenth decades of life: the Sydney Older Persons Study.Journal of neurology, neurosurgery, and psychiatry · 2004Article
- Apolipoproteins E and C1 and brain morphology in memory impaired elders.Neurogenetics · 2003Article
- The prediction and prevention of Alzheimer's disease--towards a research agenda.Journal of psychiatry & neuroscience : JPN · 1999Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging causes deterioration in various aspects of memory performance in healthy adults. Different diagnostic classifications have been proposed for use in the characterisation of mild cognitive disorders associated with aging. One of the best established of these classifications is age-associated memory impairment (AAMI). Epidemiological data suggest that AAMI is a phenomenon of normal aging rather than a sign of progression from normal aging to a pathological state such as Alzheimer's disease. A number of studies that have combined neuropsychological, neuroradiological and neurophysiological data have provided evidence of distinct characteristics in individuals with AAMI. At present, however, AAMI does not appear to describe any homogeneous group of individuals. Moreover, the neuropsychological methods used to diagnose AAMI appear to be ambiguous. Thus, AAMI appears to occur in a highly heterogeneous group of individuals, and is of questionable clinical or theoretical significance. More reliable diagnostic approaches are needed for use in studies that are attempting to identify the risk factors for dementia or to find a treatment for very early dementia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.