ArticleMedizinische Klinik (Munich, Germany : 1983)1997
[Brucellosis with fatal endotoxic shock].
Article in Medizinische Klinik (Munich, Germany : 1983), 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Brucellosis complicated by disseminated intravascular coagulation and liver injury: a case report and review of the literature.BMC infectious diseases · 2025Review
- Brucellosis presenting as septic shock.BMJ case reports · 2011Article
- Human brucellosis in Macedonia - 10 years of clinical experience in endemic region.Croatian medical journal · 2010Article
- Brucella bacteremia in a recipient of an allogeneic hematopoietic stem cell transplant: a case report.Cases journal · 2009Article
- Brucella bacteremia in patients with acute leukemia: a case series.Journal of medical case reports · 2007Article
- Lipopolysaccharides of Brucella abortus and Brucella melitensis induce nitric oxide synthesis in rat peritoneal macrophages.Infection and immunity · 2000Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundBrucellosis is a zoonosis with good prognosis in cases of early diagnosis. To make the diagnosis is still a problem today. CASE REPORT: A 60-year-old butcher was admitted with undulating fever, sweats, arthralgia and weight loss. Further examination revealed hepatosplenomegaly with laboratory findings of a hepatitis and multiple focal liver lesions shown by abdominal ultrasound and CT. Histologically, these lesions corresponded to caseous granulomas. Diagnosis of brucellosis was confirmed by detection of brucella species in prolonged incubation in blood culture. After the beginning of antibiotic resistance-tested therapy with tetracycline and quinolones, an endotoxic shock occurred during the first 24 hours of treatment and the patient died after multiorgan failure with disseminated intravascular coagulation.
conclusionIn cases of undulating fever with liver involvement, a brucellosis should be considered. Good teamwork of the internal, pathological and microbiological departments is necessary for early and correct diagnosis. This is the first report of human brucellosis in association with lethal endotoxic shock.
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