ArticleThe EMBO journal1997
Invertebrate retroviruses: ZAM a new candidate in D.melanogaster.
Article in The EMBO journal, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- piRNA Defense Against Endogenous Retroviruses.Viruses · 2024Review
- Reactivation of a somatic errantivirus and germline invasion in Drosophila ovaries.Nature communications · 2023Article
- Identification of potential new mosquito-associated viruses of adult Aedes aegypti mosquitoes from Tocantins state, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Coral-Associated Viral Assemblages From the Central Red Sea Align With Host Species and Contribute to Holobiont Genetic Diversity.Frontiers in microbiology · 2020Article
- Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasion.Genome biology · 2019Article
- Transcriptionally promiscuous "blurry" promoters in Tc1/Mobile DNA · 2019Article
- History of the discovery of a master locus producing piRNAs: the flamenco/COM locus in Drosophila melanogaster.Frontiers in genetics · 2014Review
- Distribution, evolution, and diversity of retrotransposons at the flamenco locus reflect the regulatory properties of piRNA clusters.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Article
- Functional characteristics of a highly specific integrase encoded by an LTR-retrotransposon.PloS one · 2008Article
- Article
- Molecular characterization and genomic distribution of Isis: a new retrotransposon of Drosophila buzzatii.Molecular genetics and genomics : MGG · 2007Article
- Viral particles of the endogenous retrovirus ZAM from Drosophila melanogaster use a pre-existing endosome/exosome pathway for transfer to the oocyte.Retrovirology · 2006Article
- Intercellular communication between germ line and somatic line is utilized to control the transcription of ZAM, an endogenous retrovirus from Drosophila melanogaster.Nucleic acids research · 2004Article
- Boudicca, a retrovirus-like long terminal repeat retrotransposon from the genome of the human blood fluke Schistosoma mansoni.Journal of virology · 2003Article
- Promoter competition as a mechanism of transcriptional interference mediated by retrotransposons.The EMBO journal · 2002Article
- Coupling of enhancer and insulator properties identified in two retrotransposons modulates their mutagenic impact on nearby genes.Molecular and cellular biology · 2002Article
- The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.Genome biology · 2002Article
- Relatedness of baculovirus and gypsy retrotransposon envelope proteins.BMC evolutionary biology · 2001Article
- Evolution and phylogeny of insect endogenous retroviruses.BMC evolutionary biology · 2001Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ZAM, a new retroelement of Drosophila melanogaster, was identified as a mutational insertion at the white locus. It displays all the structural features of a vertebrate retrovirus. Its three open reading frames encode predicted products resembling the products of the gag, pol and env genes of retroviruses. Its transcription gives rise to an 8.6 kb full-length RNA and a 1.7 kb spliced message for the env gene. The latter encodes an envelope protein that is typical of elements having an extracellular phase of the life cycle. The identification of a ZAM envelope retrogene provides evidence that ZAM is mobilized through a reverse trancriptional process in the germ line of flies. We report that ZAM is distributed differently among D.melanogaster strains. Two stocks out of >15 tested display a ZAM high copy number, with numerous copies distributed on chromosomal arms. This high copy number is associated with a high transcriptional rate of ZAM. The existence of these two categories of strains offers a new genetic system in which the properties of a potential invertebrate retrovirus can be tested.
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