ArticleDigestive diseases and sciences1997
Morphological characteristics, epithelial cell proliferation, and crypt fission in cecum and colon of growing pigs.
Article in Digestive diseases and sciences, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 51 citations in OpenAlex.
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- A LGR5 reporter pig model closely resembles human intestine for improved study of stem cells in disease.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023Article
- Early weaning causes small intestinal atrophy by inhibiting the activity of intestinal stem cells: involvement of Wnt/β-catenin signaling.Stem cell research & therapy · 2023Article
- Large intestinal dynamics differ between fowl and swine: Anatomical modifications, microbial collaboration, and digestive advantages from fibrolytic enzymes.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Review
- Impact of early-life feeding on local intestinal microbiota and digestive system development in piglets.Scientific reports · 2021Article
- Gastrointestinal Tract and Dietary Fiber Driven Alterations of Gut Microbiota and Metabolites in Durco × Bamei Crossbred Pigs.Frontiers in nutrition · 2021Article
- Dietary Fiber Influences Bacterial Community Assembly Processes in the Gut Microbiota of Durco × Bamei Crossbred Pig.Frontiers in microbiology · 2021Article
- Effect of pre- and post-weaning dietary supplementation with arginine and glutamine on rabbit performance and intestinal health.BMC veterinary research · 2019Article
- Article
- The role of cell proliferation and crypt fission in adenoma aggressiveness: a comparison of ileoanal pouch and rectal adenomas in familial adenomatous polyposis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2011Article
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1 author at 1 institution in 1 country.
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Abstract
Morphological characteristics and cellular proliferation were investigated in the hindgut tissue of 25 pigs ranging from 5 to 261 days of age; the three youngest pigs were unweaned. Tissue samples were taken from the cecum and from the proximal, middle, and distal part of the colon. In the young pigs a high incidence of branched crypts was observed. During the first three to four months there was an increase in crypt height and proliferative activity, as determined by the mitotic count, as well as an increase in the mucin secretion, especially the sulfomucins. Distinct regional differences were observed between the four intestinal sites. In general, the crypts were deeper and more closely spaced and the turnover time was higher in the distal part of the colon as compared to the cecum and the proximal colon. Furthermore, a greater proportion of the mucins in the middle and distal part of the colon are acidic or sulfated as compared to the cecum, where the mucins are more of the neutral type. These regional and age-related differences in morphological characteristics of the hindgut in pigs may have significance for the etiology of intestinal infections.
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