ArticleThe Journal of cell biology1997
A chromatin-associated kinesin-related protein required for normal mitotic chromosome segregation in Drosophila.
Article in The Journal of cell biology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- BUB1/KIF14 complex promotes anaplastic thyroid carcinoma progression by inducing chromosome instability.Journal of cellular and molecular medicine · 2024Article
- Acentrosomal spindles assemble from branching microtubule nucleation near chromosomes in Xenopus laevis egg extract.Nature communications · 2023Article
- SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with theFrontiers in immunology · 2022Article
- The Drosophila Forkhead/Fox transcription factor Jumeau mediates specific cardiac progenitor cell divisions by regulating expression of the kinesin Nebbish.Scientific reports · 2021Article
- Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish.Human molecular genetics · 2019Article
- KIF14 promotes cell proliferation via activation of Akt and is directly targeted by miR-200c in colorectal cancer.International journal of oncology · 2018Article
- Up-regulation of KIF14 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in cervical cancer.Bioscience reports · 2016Article
- The Ran Pathway in Drosophila melanogaster Mitosis.Frontiers in cell and developmental biology · 2015Review
- The motor protein KIF14 inhibits tumor growth and cancer metastasis in lung adenocarcinoma.PloS one · 2013Article
- CAML loss causes anaphase failure and chromosome missegregation.Cell cycle (Georgetown, Tex.) · 2009Article
- Model of chromosome motility in Drosophila embryos: adaptation of a general mechanism for rapid mitosis.Biophysical journal · 2006Article
- RNA interference-mediated silencing of mitotic kinesin KIF14 disrupts cell cycle progression and induces cytokinesis failure.Molecular and cellular biology · 2006Article
- Microtubule movements on the arms of mitotic chromosomes: polar ejection forces quantified in vitro.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers.Oncogene · 2005Article
- Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.Molecular biology of the cell · 2005Article
- The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line.The Journal of cell biology · 2003Article
- Article
- All kinesin superfamily protein, KIF, genes in mouse and human.Proceedings of the National Academy of Sciences of the United States of America · 2001Review
- A kinesin-related protein, KRP(180), positions prometaphase spindle poles during early sea urchin embryonic cell division.The Journal of cell biology · 2000Article
- The vertebrate cell kinetochore and its roles during mitosis.Trends in cell biology · 1998Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The tiovivo (tio) gene of Drosophila encodes a kinesin-related protein, KLP38B, that colocalizes with condensed chromatin during cell division. Wild-type function of the tio gene product KLP38B is required for normal chromosome segregation during mitosis. Mitotic cells in tio larval brains displayed circular mitotic figures, increased ploidy, and abnormal anaphase figures. KLP38B mRNA is maternally provided and expressed in cells about to undergo division. We propose that KLP38B, perhaps redundantly with other chromosome-associated microtubule motor proteins, contributes to interactions between chromosome arms and microtubules important for establishing bipolar attachment of chromosomes and assembly of stable bipolar spindles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.