ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1997
Effects of sleep on wake-induced c-fos expression.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 79 citations in OpenAlex.
- Prefrontal coding of learned and inferred knowledge during REM and NREM sleep.Nature communications · 2024Article
- Searching for sleep in all the right places: My career in sleep research.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Visual light flicker stimulation: enhancing alertness in sleep-deprived rats.Frontiers in neuroscience · 2024Article
- Structure and function differences in the prelimbic cortex to basolateral amygdala circuit mediate trait vulnerability in a novel model of acute social defeat stress in male mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Dihydropyridine calcium blockers do not interfere with non-rapid eye movement sleep.Frontiers in neuroscience · 2022Article
- Sleep Is for Forgetting.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Review
- Optogenetic activation of melanin-concentrating hormone neurons increases non-rapid eye movement and rapid eye movement sleep during the night in rats.The European journal of neuroscience · 2016Article
- Protective Effects of Otophylloside N on Pentylenetetrazol-Induced Neuronal Injury In vitro and In vivo.Frontiers in pharmacology · 2016Article
- Electroencephalographic variation during end maintenance and emergence from surgical anesthesia.PloS one · 2014Article
- Control of sleep and wakefulness.Physiological reviews · 2012Review
- Highly specific role of hypocretin (orexin) neurons: differential activation as a function of diurnal phase, operant reinforcement versus operant avoidance and light level.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Fos expression in arousal and reward areas of the brain in grass rats following induced wakefulness.Physiology & behavior · 2011Article
- Maturation of sleep homeostasis in developing rats: a role for preoptic area neurons.American journal of physiology. Regulatory, integrative and comparative physiology · 2011Article
- Activation of cortical interneurons during sleep: an anatomical link to homeostatic sleep regulation?Trends in neurosciences · 2011Article
- Circadian and homeostatic regulation of structural synaptic plasticity in hypocretin neurons.Neuron · 2010Article
- Metabolic response of the cerebral cortex following gentle sleep deprivation and modafinil administration.Sleep · 2010Article
- A combined method of laser capture microdissection and X-Gal histology to analyze gene expression in c-Fos-specific neurons.Journal of neuroscience methods · 2010Article
- Neural activation in arousal and reward areas of the brain in day-active and night-active grass rats.Neuroscience · 2010Article
- Cognitive neuroscience of sleep.Progress in brain research · 2010Review
- c-Fos protein expression is increased in cholinergic neurons of the rodent basal forebrain during spontaneous and induced wakefulness.Brain research bulletin · 2009Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
We investigated the effects of sleep on wake-induced c-fos expression in the cerebral cortex of rats and c-fos-lacZ transgenic mice. In the cortex of rats, the levels of c-Fos, detected both by immunocytochemistry and Western blot, remained high during 6 or 12 hr of enforced wakefulness but declined rapidly (within 1 hr) with increasing time of recovery sleep. Similarly, in the transgenic mice in which lacZ expression is driven from the c-fos promoter, beta-galactosidase activity was high after enforced wakefulness and declined with increasing amounts of sleep. These results suggest that the decrease in c-Fos protein in cortical neurons during sleep may be attributable to cessation of c-fos expression, activation of a process that degrades the wake-induced c-Fos, or both.
Indexed as
Identifiers
9391027PMC6573405W1941928119What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.