ArticleGenetics1997
UV- and gamma-radiation sensitive mutants of Arabidopsis thaliana.
Article in Genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- Spatially heterogeneous selection and inter-varietal differentiation maintain population structure and local adaptation in a widespread conifer.BMC ecology and evolution · 2024Article
- Genomics of ecological adaptation in Canary IslandEcology and evolution · 2024Article
- Article
- DNA damage and repair in plants - from models to crops.Frontiers in plant science · 2015Review
- Arabidopsis DNA polymerase lambda mutant is mildly sensitive to DNA double strand breaks but defective in integration of a transgene.Frontiers in plant science · 2015Article
- Genomic stability in response to high versus low linear energy transfer radiation in Arabidopsis thaliana.Frontiers in plant science · 2014Article
- Article
- Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair.Journal of nucleic acids · 2010Article
- Suppressor of gamma response 1 (SOG1) encodes a putative transcription factor governing multiple responses to DNA damage.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- DNA ligase 1 deficient plants display severe growth defects and delayed repair of both DNA single and double strand breaks.BMC plant biology · 2009Article
- Inefficient double-strand DNA break repair is associated with increased fasciation in Arabidopsis BRCA2 mutants.Journal of experimental botany · 2009Article
- UV-induced DNA damage promotes resistance to the biotrophic pathogen Hyaloperonospora parasitica in Arabidopsis.Plant physiology · 2008Article
- Adaptation and impairment of DNA repair function in pollen of Betula verrucosa and seeds of Oenothera biennis from differently radionuclide-contaminated sites of Chernobyl.Annals of botany · 2008Article
- Delimitation of the chromosomal region for a quantitative trait locus, qUVR- 10, conferring resistance to ultraviolet-B radiation in rice (Oryza sativa L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2004Article
- A DNA-damage-induced cell cycle checkpoint in Arabidopsis.Genetics · 2003Article
- Role of the AtRad1p endonuclease in homologous recombination in plants.EMBO reports · 2002Article
- An ultraviolet-B-resistant mutant with enhanced DNA repair in Arabidopsis.Plant physiology · 2002Article
- Repair of damaged bases.The arabidopsis book · 2002Article
- An Arabidopsis mutant tolerant to lethal ultraviolet-B levels shows constitutively elevated accumulation of flavonoids and other phenolics.Plant physiology · 2001Article
- The Arabidopsis UVH1 gene is a homolog of the yeast repair endonuclease RAD1.Plant physiology · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arabidopsis seedlings repair UV-induced DNA damage via light-dependent and independent pathways. The mechanism of the "dark repair" pathway is still unknown. To determine the number of genes required for dark repair and to investigate the substrate-specificity of this process we isolated mutants with enhanced sensitivity to UV radiation in the absence of photoreactivating light. Seven independently derived UV sensitive mutants were isolated from an EMS-mutagenized population. These fell into six complementation groups, two of which (UVR1 and UVH1) have previously been defined. Four of these mutants are defective in the dark repair of UV-induced pyrimidine [6-4]pyrimidinone dimers. These four mutant lines are sensitive to the growth-inhibitory effects of gamma radiation, suggesting that this repair pathway is also involved in the repair of some type of gamma-induced DNA damage product. The requirement for the coordinate action of several different gene products for effective repair of pyrimidine dimers, as well as the nonspecific nature of the repair activity, is consistent with nucleotide excision repair mechanisms previously described in Saccharomyces cerevisiae and nonplant higher eukaryotes and inconsistent with substrate-specific base excision repair mechanisms found in some bacteria, bacteriophage, and fungi.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.