Evidence map›Paper›PMID 9383064›Full record

ArticleGenetics1997

A cluster of cuticle protein genes of Drosophila melanogaster at 65A: sequence, structure and evolution.

J P Charles, C Chihara, S Nejad, L M Riddiford

Erratum issuedAbstract read
In one paragraph

Article in Genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  10. Article
  11. No slave to sex.Proceedings. Biological sciences · 2003
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4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

4 authors.

J P CharlesDepartment of Zoology, University of Washington, Seattle 98195-1800, USA.
C Chihara
S Nejad
L M Riddiford

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 36-kb genomic DNA segment of the Drosophila melanogaster genome containing 12 clustered cuticle genes has been mapped and partially sequenced. The cluster maps at 65A 5-6 on the left arm of the third chromosome, in agreement with the previously determined location of a putative cluster encompassing the genes for the third instar larval cuticle proteins LCP5, LCP6 and LCP8. This cluster is the largest cuticle gene cluster discovered to date and shows a number of surprising features that explain in part the genetic complexity of the LCP5, LCP6 and LCP8 loci. The genes encoding LCP5 and LCP8 are multiple copy genes and the presence of extensive similarity in their coding regions gives the first evidence for gene conversion in cuticle genes. In addition, five genes in the cluster are intronless. Four of these five have arisen by retroposition. The other genes in the cluster have a single intron located at an unusual location for insect cuticle genes.

Indexed as

Multigene FamilyAnimalsBase SequenceDNA, ComplementaryDrosophila melanogasterEvolution, MolecularGene DosageGenomeInsect ProteinsMolecular Sequence DataSequence Homology, Nucleic Acidcuticle proteins, insectsDNA, ComplementaryInsect Proteins

Identifiers

PMID9383064
PMCPMC1208245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.