ArticleEnvironmental health perspectives1997
Residential exposure to plasticizers and its possible role in the pathogenesis of asthma.
Article in Environmental health perspectives, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 239 citations in OpenAlex.
- A systematic review on the adverse health effects of di-2-ethylhexyl phthalate.Environmental science and pollution research international · 2016Pooled it
- The role of exposure to phthalates from polyvinyl chloride products in the development of asthma and allergies: a systematic review and meta-analysis.Environmental health perspectives · 2008Pooled it
- Article
- A Study of the Relationship between Phthalate Exposure and the Occurrence of Adult Asthma in Taiwan.Molecules (Basel, Switzerland) · 2023Article
- Phthalate Metabolites in Urine of Chinese Children and Their Association with Asthma and Allergic Symptoms.International journal of environmental research and public health · 2022Article
- An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods.Environmental geochemistry and health · 2022Review
- Characteristics of dust-phase phthalates in dormitory, classroom, and home and non-dietary exposure in Beijing, China.Environmental science and pollution research international · 2021Article
- Hexabromocyclododecane diastereoisomers in surface sediments from river drainage basins of Shanghai, China: occurrence, distribution, and mass inventory.Environmental science and pollution research international · 2015Article
- Home renovation, family history of atopy, and respiratory symptoms and asthma among children living in China.American journal of public health · 2014Article
- Phthalate exposure and health-related outcomes in specific types of work environment.International journal of environmental research and public health · 2014Article
- The association between urinary phthalates and lung function.Journal of occupational and environmental medicine · 2014Article
- Role of Ca/CaN/NFAT signaling in IL-4 expression by splenic lymphocytes exposed to phthalate (2-ethylhexyl) ester in spleen lymphocytes.Molecular biology reports · 2014Article
- The distribution of phthalate esters in indoor dust of Palermo (Italy).Environmental geochemistry and health · 2013Article
- Urinary biomarkers for phthalates associated with asthma in Norwegian children.Environmental health perspectives · 2013Article
- Characteristics and assessment of phthalate esters in urban dusts in Guangzhou city, China.Environmental monitoring and assessment · 2012Article
- Biological monitoring of exposure to di(2-ethylhexyl) phthalate in six French factories: a field study.International archives of occupational and environmental health · 2011Article
- Indoor air pollution: an old problem with new challenges.International journal of environmental research and public health · 2009Article
- Phthalate ester-induced thymic stromal lymphopoietin mediates allergic dermatitis in mice.Immunology · 2009Article
- Antimicrobial and Cytotoxic Activity of Di-(2-ethylhexyl) Phthalate and Anhydrosophoradiol-3-acetate Isolated from Calotropis gigantea (Linn.) Flower.Mycobiology · 2009Article
- Concentrations of phthalate metabolites in milk, urine, saliva, and Serum of lactating North Carolina women.Environmental health perspectives · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plasticizer di(2-ethylhexyl) phthalate (DEHP) is widely used in building materials. DEHP is identified as the major plasticizer exposure in dwellings. We provide evidence that inhalation exposure to DEHP as aerosols adsorbed to particulate matter is as important, or more important, than vapor phase exposure. The particulate inhalation exposure to DEHP is considered to be significant due to its low clearance and extensive penetration into the pulmonary region. DEHP is capable of creating high local concentrations in the airways at the deposition site with subsequent local effects. The proposed mechanism of effect states that mono(2-ethylhexyl) phthalate (MEHP), the primary hydrolysis product of DEHP, mimics the inducing prostaglandins (PG) PGD(2), 9alpha,11betaPGF2, and PGF2alpha, and thromboxanes in the lungs, thereby increasing the risk of inducing inflammation in the airways, which is a characteristic of asthma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.