Evidence map›Paper›PMID 9371799›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1997

Yeast microarrays for genome wide parallel genetic and gene expression analysis.

D A Lashkari, J L DeRisi, J H McCusker, A F Namath, C Gentile, S Y Hwang, P O Brown, R W Davis

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 680 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. International journal of molecular sciences · 2022
    Review
  5. Review
  6. Gosling: A Grammar-based Toolkit for Scalable and Interactive Genomics Data Visualization.IEEE transactions on visualization and computer graphics · 2022
    Article
  7. Article
  8. Genetic interaction between RLM1 and F-box motif encoding gene SAF1 contributes to stress response in Saccharomyces cerevisiae.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021
    Article
  9. DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Genome-scale transcriptional dynamics and environmental biosensing.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  11. Review
  12. Gene Expression ofInternational journal of molecular sciences · 2019
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Cell type-specific transcriptome profiling in mammalian brains.Frontiers in bioscience (Landmark edition) · 2016
    Review
  20. Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

D A LashkariDepartment of Genetics, Stanford University, CA 94305, USA.
J L DeRisi
J H McCusker
A F Namath
C Gentile
S Y Hwang
P O Brown
R W Davis
Duke University · USStanford University · US

Funding

WHOLE YEAST GENOME TRANSCRIPTIONAL AND FUNCTIONAL GENE MAPS--A FEASIBILITY STUDYP01HG000205 · NHGRI · STANFORD UNIVERSITY · PI DAVIS, RONALD WAYNE, HOWE, ROGER THOMAS · 1990 to 2016
$120.9M
NHGRI NIH HHS P01 HG000205NHGRI NIH HHS P0/HG00205
6 · The paper itself

Abstract

We have developed high-density DNA microarrays of yeast ORFs. These microarrays can monitor hybridization to ORFs for applications such as quantitative differential gene expression analysis and screening for sequence polymorphisms. Automated scripts retrieved sequence information from public databases to locate predicted ORFs and select appropriate primers for amplification. The primers were used to amplify yeast ORFs in 96-well plates, and the resulting products were arrayed using an automated micro arraying device. Arrays containing up to 2,479 yeast ORFs were printed on a single slide. The hybridization of fluorescently labeled samples to the array were detected and quantitated with a laser confocal scanning microscope. Applications of the microarrays are shown for genetic and gene expression analysis at the whole genome level.

Indexed as

Gene ExpressionGenome, FungalCold TemperatureDNA, ComplementaryDNA PrimersGalactoseGenotypeGlucoseHeat-Shock ResponseOpen Reading FramesSaccharomyces cerevisiaeDNA, ComplementaryDNA PrimersGalactoseGlucose

Identifiers

PMID9371799
PMCPMC24262
OpenAlexW2113310577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.