Evidence map›Paper›PMID 9371744›Full record

ArticleGenome research1997

Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.

K P Brady, L B Rowe, H Her, T J Stevens, J Eppig, D J Sussman, J Sikela, D R Beier

Open access · hybridAbstract read
In one paragraph

Article in Genome research, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

K P BradyDivision of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
L B Rowe
H Her
T J Stevens
J Eppig
D J Sussman
J Sikela
D R Beier
University of Maryland, Baltimore · US

Funding

MOUSE GENETIC MAPPING RESOURCER01HG000941 · NHGRI · JACKSON LABORATORY · PI EPPIG, JANAN T. · 1993 to 2001
$863k
EXPRESSED-SEQUENCE MAP OF THE MOUSE GENOMER01HG000951 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI BEIER, DAVID R. · 1993 to 1995
–
NHGRI NIH HHS HG00941NHGRI NIH HHS HG00951
6 · The paper itself

Abstract

We have demonstrated previously that noncoding sequences of genes are a robust source of polymorphisms between mouse species when tested using single-strand conformation polymorphism (SSCP) analysis, and that these polymorphisms are useful for genetic mapping. In this report we demonstrate that presumptive 3'-untranslated region sequence obtained from expressed sequence tags (ESTs) can be analyzed in a similar fashion, and we have used this approach to map 262 loci using an interspecific backcross. These results demonstrate SSCP analysis of genes or ESTs is a simple and efficient means for the genetic localization of transcribed sequences, and is furthermore an approach that is applicable to any system for which there is sufficient sequence polymorphism.

Indexed as

Chromosome MappingPolymorphism, Single-Stranded ConformationalAnimalsCrosses, GeneticDNA Mutational AnalysisGene LibraryGenetic MarkersMiceMice, Inbred AKRMice, Inbred C3HMice, Inbred C57BLMice, Inbred DBAMice, Inbred StrainsMuridaeSequence Tagged SitesTranscription, GeneticGenetic Markers

Identifiers

PMID9371744
PMCPMC310685
OpenAlexW1834691444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.