Evidence map›Paper›PMID 9371743›Full record

ArticleGenome research1997

High throughput fingerprint analysis of large-insert clones.

M A Marra, T A Kucaba, N L Dietrich, E D Green, B Brownstein, R K Wilson, K M McDonald, L W Hillier, J D McPherson, R H Waterston

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 163 papers.

0numbers the graph read from it
0cells of the map it votes in
163citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

163 citing papers in PubMed, 402 citations in OpenAlex.

  1. Article
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  11. The control of seed oil polyunsaturate content in the polyploid crop speciesMolecular breeding : new strategies in plant improvement · 2014
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  16. Current status and future perspectives for sequencing livestock genomes.Journal of animal science and biotechnology · 2012
    Article
  17. Article
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  19. Article
  20. Article

103 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

M A MarraWashington University School of Medicine, Genome Sequencing Center, St. Louis, Missouri 63108, USA. mmarra@watson.wustl.edu
T A Kucaba
N L Dietrich
E D Green
B Brownstein
R K Wilson
K M McDonald
L W Hillier
J D McPherson
R H Waterston
National Institutes of Health · US

Funding

YEAST SEQUENCINGP01HG000956 · NHGRI · WASHINGTON UNIVERSITY · PI WATERSTON, ROBERT H · 1993 to 2003
$2.0M
LARGE SCALE HUMAN SEQUENCINGP50HG001458 · NHGRI · WASHINGTON UNIVERSITY · PI WATERSTON, ROBERT H · 1996 to 1999
–
NHGRI NIH HHS 1P50HG01458NHGRI NIH HHS 5P01HG00956NHGRI NIH HHS P01 HG000956
6 · The paper itself

Abstract

As part of the Human Genome Project, the Washington University Genome Sequencing Center has commenced systematic sequencing of human chromsome 7. To organize and supply the effort, we have undertaken the construction of sequence-ready physical maps for defined chromosomal intervals. Map construction is a serial process composed of three main activities. First, candidate STS-positive large-insert PAC and BAC clones are identified. Next, these candidate clones are subjected to fingerprint analysis. Finally, the fingerprint data are used to assemble sequence-ready maps. The fingerprinting method we have devised is key to the success of the overall approach. We present here the details of the method and show that the fingerprints are of sufficient quality to permit the construction of megabase-size contigs in defined regions of the human genome. We anticipate that the high throughput and precision characteristic of our fingerprinting method will make it of general utility.

Indexed as

Chromosomes, Human, Pair 7Human Genome ProjectBase SequenceChromosome MappingCloning, MolecularDNA FingerprintingGenetic MarkersHumansRestriction MappingGenetic Markers

Identifiers

PMID9371743
PMCPMC310686
OpenAlexW2169885026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.