ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1997
Release sites and calcium channels in hair cells of the chick's cochlea.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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Who cites it
55 citing papers in PubMed, 117 citations in OpenAlex.
- Formation, Organization, and Maintenance of Synaptic Vesicle Pools: From Molecules to Structure and Dynamics.Advances in neurobiology · 2026Review
- Patterned pre-sensory spontaneous activity drives the structural refinement of developing cochlear ribbon synapses.Frontiers in synaptic neuroscience · 2026Article
- Article
- Histological Correlates of Auditory Nerve Injury from Kainic Acid in the Budgerigar (Melopsittacus undulatus).Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Comparative study of ionic currents and exocytosis in hair cells of the basilar and amphibian papilla in bullfrogs.Frontiers in cellular neuroscience · 2022Article
- VGLUT3-p.A211V variant fuses stereocilia bundles and elongates synaptic ribbons.The Journal of physiology · 2021Article
- Piccolo is essential for the maintenance of mouse retina but not cochlear hair cell function.Aging · 2021Article
- Vesicular Glutamatergic Transmission in Noise-Induced Loss and Repair of Cochlear Ribbon Synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- In Vivo Ribbon Mobility and Turnover of Ribeye at Zebrafish Hair Cell Synapses.Scientific reports · 2017Article
- Ion channel noise can explain firing correlation in auditory nerves.Journal of computational neuroscience · 2016Article
- Hair cells use active zones with different voltage dependence of Ca2+ influx to decompose sounds into complementary neural codes.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Relating structure and function of inner hair cell ribbon synapses.Cell and tissue research · 2015Review
- Synaptic calcium regulation in hair cells of the chicken basilar papilla.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Specialized postsynaptic morphology enhances neurotransmitter dilution and high-frequency signaling at an auditory synapse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Localization and proteomic characterization of cholesterol-rich membrane microdomains in the inner ear.Journal of proteomics · 2014Article
- Modeling the influence of short term depression in vesicle release and stochastic calcium channel gating on auditory nerve spontaneous firing statistics.Frontiers in computational neuroscience · 2014Article
- Response properties from turtle auditory hair cell afferent fibers suggest spike generation is driven by synchronized release both between and within synapses.Journal of neurophysiology · 2013Article
- Refractoriness enhances temporal coding by auditory nerve fibers.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Electrical tuning and transduction in short hair cells of the chicken auditory papilla.Journal of neurophysiology · 2013Article
- Presynaptic CaV1.3 channels regulate synaptic ribbon size and are required for synaptic maintenance in sensory hair cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Rapid transmitter release at synapses depends on the close proximity of voltage-gated calcium channels (VGCCs). In mechanosensory hair cells of the vertebrate inner ear, dihydropyridine-sensitive VGCCs may be preferentially expressed at release sites to support transmitter release. In support of this hypothesis we have found that whole-cell current through VGCCs covaried with afferent innervation density among hair cells of the chick's basilar papilla (the avian analog of the mammalian Organ of Corti). The size as well as number of presynaptic dense bodies (PDBs) around which transmitter vesicles cluster varied systematically among equivalent populations of hair cells examined with electron microscopy. The total number of VGCCs was correlated with total release area (PDB cross-sectional area x the number of PDBs) among neurally located (tall) hair cells. Abneural, short hair cells with little or no afferent contact expressed a low number of VGCCs independent of release area. The implication is that hair cells augment calcium channel expression by adding release sites and by making release sites larger. This suggests further that aspects of hair cell excitability, such as electrical tuning, could depend on the synaptic architecture of each cell.
Indexed as
Identifiers
9364060PMC6573622W1517515161What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.