ArticleMolecular biology of the cell1997
Transport of myosin II to the equatorial region without its own motor activity in mitotic Dictyostelium cells.
Article in Molecular biology of the cell, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 73 citations in OpenAlex.
- Actomyosin dynamics in detached cells: linking clutch model to cell migration and cytokinesis.BMC molecular and cell biology · 2025Article
- Article
- Myosin-II-mediated directional migration of Dictyostelium cells in response to cyclic stretching of substratum.Biophysical journal · 2013Article
- Cell-scale dynamic recycling and cortical flow of the actin-myosin cytoskeleton for rapid cell migration.Biology open · 2013Article
- A mechanosensory system governs myosin II accumulation in dividing cells.Molecular biology of the cell · 2012Article
- Deconvolution of the cellular force-generating subsystems that govern cytokinesis furrow ingression.PLoS computational biology · 2012Article
- Stable and dynamic microtubules coordinately shape the myosin activation zone during cytokinetic furrow formation.The Journal of cell biology · 2008Article
- A mechanosensory system controls cell shape changes during mitosis.Cell cycle (Georgetown, Tex.) · 2007Review
- A global, myosin light chain kinase-dependent increase in myosin II contractility accompanies the metaphase-anaphase transition in sea urchin eggs.Molecular biology of the cell · 2006Article
- Microtubule-dependent transport and organization of sarcomeric myosin during skeletal muscle differentiation.The EMBO journal · 2005Article
- Cytokinesis depends on the motor domains of myosin-II in fission yeast but not in budding yeast.Molecular biology of the cell · 2005Article
- Biological, biochemical, and kinetic effects of mutations of the cardiomyopathy loop of Dictyostelium myosin II: importance of ALA400.The Journal of biological chemistry · 2005Article
- The stress and strain of cytokinesis.Trends in cell biology · 2005Review
- Novel myosin heavy chain kinase involved in disassembly of myosin II filaments and efficient cleavage in mitotic dictyostelium cells.Molecular biology of the cell · 2002Article
- Cytokinesis in eukaryotes.Microbiology and molecular biology reviews : MMBR · 2002Review
- Quantitation of the distribution and flux of myosin-II during cytokinesis.BMC cell biology · 2002Article
- Localization of fission yeast type II myosin, Myo2, to the cytokinetic actin ring is regulated by phosphorylation of a C-terminal coiled-coil domain and requires a functional septation initiation network.Molecular biology of the cell · 2001Article
- Contraction and polymerization cooperate to assemble and close actomyosin rings around Xenopus oocyte wounds.The Journal of cell biology · 2001Article
- Myosin II dynamics and cortical flow during contractile ring formation in Dictyostelium cells.The Journal of cell biology · 2001Article
- A structural model for phosphorylation control of Dictyostelium myosin II thick filament assembly.The Journal of cell biology · 1999Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluorescently labeled myosin moved and accumulated circumferentially in the equatorial region of dividing Dictyostelium cells within a time course of 4 min, followed by contraction of the contractile ring. To investigate the mechanism of this transport process, we have expressed three mutant myosins that cannot hydrolyze ATP in myosin null cells. Immunofluorescence staining showed that these mutant myosins were also correctly transported to the equatorial region, although no contraction followed. The rates of transport, measured using green fluorescent protein-fused myosins, were indistinguishable between wild-type and mutant myosins. These observations demonstrate that myosin is passively transported toward the equatorial region and incorporated into the forming contractile ring without its own motor activity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.