Loss of heterozygosity or: how I learned to stop worrying and love mitotic recombination.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

35 citing papers in PubMed.

1. [The two-in-one hit model of the short-cut carcinogenesis of colorectal carcinomas in MLH1-associated Lynch syndrome].Pathologie (Heidelberg, Germany) · 2023
   Review
2. Polyploidy as an Adaptation against Loss of Heterozygosity in Cancer.International journal of molecular sciences · 2022
   Article
3. Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain.Cancer discovery · 2022
   Article
4. Whole body transcriptomes and new insights into the biology of the tick Ixodes ricinus.Parasites & vectors · 2018
   Article
5. Homologous recombination occurs frequently at innate GT microsatellites in normal somatic and germ cells in vivo.BMC genomics · 2018
   Article
6. Increased LOH due to Defective Sister Chromatid Cohesion Is due Primarily to Chromosomal Aneuploidy and not Recombination.G3 (Bethesda, Md.) · 2017
   Article
7. Functional Validation of Rare Human Genetic Variants Involved in Homologous Recombination Using Saccharomyces cerevisiae.PloS one · 2015
   Article
8. The onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either allele.Cell death and differentiation · 2014
   Article
9. Biological insights into BRAFOncoimmunology · 2013
   Article
10. Loss of heterozygosity drives clonal diversity of Phytophthora capsici in China.PloS one · 2013
    Article
11. Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells.Mutation research · 2011
    Article
12. Homologous recombination conserves DNA sequence integrity throughout the cell cycle in embryonic stem cells.Stem cells and development · 2011
    Article
13. Dissecting loss of heterozygosity (LOH) in neurofibromatosis type 1-associated neurofibromas: Importance of copy neutral LOH.Human mutation · 2011
    Article
14. Review of chromium (VI) apoptosis, cell-cycle-arrest, and carcinogenesis.Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews · 2010
    Review
15. Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes.PLoS genetics · 2010
    Article
16. Deleterious mutations and selection for sex in finite diploid populations.Genetics · 2010
    Article
17. High-resolution DNA copy number and gene expression analyses distinguish chromophobe renal cell carcinomas and renal oncocytomas.BMC cancer · 2009
    Article
18. Emerging paradigms in cancer genetics: some important findings from high-density single nucleotide polymorphism array studies.Cancer research · 2009
    Review
19. Interchromosomal crossover in human cells is associated with long gene conversion tracts.Molecular and cellular biology · 2007
    Article
20. Mitotic recombination counteracts the benefits of genetic segregation.Proceedings. Biological sciences · 2007
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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