ArticleThe Plant cell1997
Recombination occurs uniformly within the bronze gene, a meiotic recombination hotspot in the maize genome.
Article in The Plant cell, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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Who cites it
81 citing papers in PubMed.
- Natural variation modifies centromere-proximal meiotic crossover frequency and segregation distortion in Arabidopsis thaliana.Genetics · 2026Article
- An overview of recent advances on wheat homologous and homoeologous recombination.Journal of experimental botany · 2026Review
- Enhancing local meiotic crossovers in Arabidopsis and maize through juxtaposition of heterozygous and homozygous regions.Nature plants · 2025Article
- Diversity in Recombination Hotspot Characteristics and Gene Structure Shape Fine-Scale Recombination Patterns in Plant Genomes.Molecular biology and evolution · 2024Article
- Intragenic Meiotic Crossovers Generate Novel Alleles with Transgressive Expression Levels.Molecular biology and evolution · 2018Article
- Where to Cross Over? Defining Crossover Sites in Plants.Frontiers in genetics · 2018Review
- A Critical Assessment of 60 Years of Maize Intragenic Recombination.Frontiers in plant science · 2018Review
- LTR Retrotransposons Show Low Levels of Unequal Recombination and High Rates of Intraelement Gene Conversion in Large Plant Genomes.Genome biology and evolution · 2017Article
- High-Resolution Mapping of Crossover Events in the Hexaploid Wheat Genome Suggests a Universal Recombination Mechanism.Genetics · 2017Article
- Targeted recombination between homologous chromosomes for precise breeding in tomato.Nature communications · 2017Article
- Complexity of genetic mechanisms conferring nonuniformity of recombination in maize.Scientific reports · 2017Article
- Article
- Polarized gene conversion at the bz locus of maize.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana.eLife · 2013Article
- Testing for the footprint of sexually antagonistic polymorphisms in the pseudoautosomal region of a plant sex chromosome pair.Genetics · 2013Article
- Patterns and evolution of nucleotide landscapes in seed plants.The Plant cell · 2012Article
- Fine-scale population recombination rates, hotspots, and correlates of recombination in the Medicago truncatula genome.Genome biology and evolution · 2012Article
- Molecular characterization of a genomic interval with highly uneven recombination distribution on maize chromosome 10 L.Genetica · 2011Article
- Variation in crossover rates across a 3-Mb contig of bread wheat (Triticum aestivum) reveals the presence of a meiotic recombination hotspot.Chromosoma · 2011Article
- Gene conversion in angiosperm genomes with an emphasis on genes duplicated by polyploidization.Genes · 2011Article
21 more citing papers are in PubMed but not listed here.
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2 authors.
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Abstract
The bronze (bz) gene is a recombinational hotspot in the maize genome: its level of meiotic recombination per unit of physical length is > 100-fold higher than the genome's average and is the highest of any plant gene analyzed to date. Here, we examine whether recombination is also unevenly distributed within the bz gene. In yeast genes, recombination (conversion) is polarized, being higher at the end of the gene where recombination is presumably initiated. We have analyzed products of meiotic recombination between heteroallelic pairs of bz mutations in both the presence and absence of heterologies and have sequenced the recombination junction in 130 such Bz intragenic recombinants. We have found that in the absence of heterologies, recombination is proportional to physical distance across the bz gene. The simplest interpretation for this lack of polarity is that recombination is initiated randomly within the gene. Insertion mutations affect the frequency and distribution of intragenic recombination events at bz, creating hotspots and coldspots. Single base pair heterologies also affect recombination, with fewer recombination events than expected by chance occurring in regions of the bz gene with a high density of heterologies. We also provide evidence that meiotic recombination in maize is conservative, that is, it does not introduce changes, and that meiotic conversion tracts are continuous and similar in size to those in yeast.
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