Evidence map›Paper›PMID 9336670›Full record

ReviewClinical microbiology reviews1997

Helicobacter pylori.

B E Dunn, H Cohen, M J Blaser

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 442 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
442citing papers in PubMed, 8 pooled it
46.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

442 citing papers in PubMed, 8 syntheses or guidelines pooled it, 1,065 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. A Comprehensive Survey of the Relationship betweenArchives of Iranian medicine · 2022
    Pooled it
  4. Pooled it
  5. N-acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication.The Cochrane database of systematic reviews · 2019
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Article
  11. Frequency ofCanadian liver journal · 2026
    Article
  12. Article
  13. The role of p38 MAPK in acteoside-mediated gastric ulcer protection.International journal of medical sciences · 2026
    Article
  14. Helicobacter pylori outer membrane vesicle-induced hsa-miR-302a-3p and hsa-miR-184 promote the occurrence and development of gastric cancer.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  15. Article
  16. On the Role of Food in the Transmission ofFoods (Basel, Switzerland) · 2025
    Review
  17. Article
  18. Crystal structure of dihydroorotate dehydrogenase from Helicobacter pylori with bound flavin mononucleotide.Acta crystallographica. Section F, Structural biology communications · 2025
    Article
  19. Article
  20. Article

382 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

B E DunnDepartment of Pathology, Medical College of Wisconsin, Milwaukee 53226-0509, USA.
H Cohen
M J Blaser
Medical College of Wisconsin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori is a gram-negative bacterium which causes chronic gastritis and plays important roles in peptic ulcer disease, gastric carcinoma, and gastric lymphoma. H. pylori has been found in the stomachs of humans in all parts of the world. In developing countries, 70 to 90% of the population carries H. pylori. In developed countries, the prevalence of infection is lower. There appears to be no substantial reservoir of H. pylori aside from the human stomach. Transmission can occur by iatrogenic, fecal-oral, and oral-oral routes. H. pylori is able to colonize and persist in a unique biological niche within the gastric lumen. All fresh isolates of H. pylori express significant urease activity, which appears essential to the survival and pathogenesis of the bacterium. A variety of tests to diagnose H. pylori infection are now available. Histological examination of gastric tissue, culture, rapid urease testing, DNA probes, and PCR analysis, when used to test gastric tissue, all require endoscopy. In contrast, breath tests, serology, gastric juice PCR, and urinary excretion of [15N]ammonia are noninvasive tests that do not require endoscopy. In this review, we highlight advances in the detection of the presence of the organism and methods of differentiating among types of H. pylori, and we provide a background for appropriate chemotherapy of the infection.

Indexed as

Anti-Bacterial AgentsAntibodies, BacterialBacterial VaccinesDisease Transmission, InfectiousEndoscopyGastric MucosaGastritisGenes, BacterialGenome, BacterialHelicobacter InfectionsHelicobacter pyloriHumansPolymerase Chain ReactionVaccinationAnti-Bacterial AgentsAntibodies, BacterialBacterial Vaccines

Identifiers

PMID9336670
PMCPMC172942
OpenAlexW4211017205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.