Evidence map›Paper›PMID 9335611›Full record

ArticleGenetics1997

Developmental quantitative genetics, conditional epigenetic variability and growth in mice.

W R Atchley, J Zhu

Abstract read
In one paragraph

Article in Genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

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  11. E-Index for Differentiating Complex Dynamic Traits.BioMed research international · 2016
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  20. Dynamic QTL analysis of linolenic acid content in different developmental stages of soybean seed.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

W R AtchleyDepartment of Genetics, North Carolina State University, Raleigh 27695-7614, USA. atchley@ncsu.edu
J Zhu

Funding

THEORETICAL QUANTITATIVE GENETICSP01GM045344 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI MACKAY, TRUDY F · 1991 to 2005
$7.2M
THEORETICAL POPULATION GENETICSR01GM032518 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WEIR, BRUCE S. · 1985 to 1995
–
NIGMS NIH HHS GM-32518NIGMS NIH HHS GM-45344
6 · The paper itself

Abstract

Ontogenetic variation in the causal components of phenotypic variability and covariability is described for body weight and tail length in mice derived from a full 7 x 7 diallel cross. Age-related changes in additive, dominance, sex-linked and maternal variance and covariance between 14 and 70 days of age are described. Age-specific variance components at time t are conditioned on the causal genetic effects at time (t - 1). This procedure demonstrates the generation of significant episodes of new genetic variation arising at specific intervals during ontogeny. These episodes of new genetic variation are placed in the context of epigenetic models in developmental quantitative genetics. These results are also concordant on recent findings on age-specific gene expression in mouse growth as shown by QTL analyses.

Indexed as

Genetic VariationAnimalsBody WeightFemaleMaleMiceMice, Inbred StrainsPhenotypeQuantitative Trait, HeritableSpecies SpecificityTail

Identifiers

PMID9335611
PMCPMC1208196

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.