ArticleGenetics1997
A mutation in an HSP90 gene affects the sexual cycle and suppresses vegetative incompatibility in the fungus Podospora anserina.
Article in Genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 49 citations in OpenAlex.
- Comparative transcriptome analysis revealed genes involved in the fruiting body development ofPeerJ · 2020Article
- Potential molecular mechanisms for fruiting body formation of Cordyceps illustrated in the case ofMycology · 2017Article
- Heat shock protein 90 is required for sexual and asexual development, virulence, and heat shock response in Fusarium graminearum.Scientific reports · 2016Article
- The fungus-specific HET domain mediates programmed cell death in Podospora anserina.Eukaryotic cell · 2007Article
- Sexual and vegetative compatibility genes in the aspergilli.Studies in mycology · 2007Article
- Control of canalization and evolvability by Hsp90.PloS one · 2006Article
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- Comparative analysis of programmed cell death pathways in filamentous fungi.BMC genomics · 2005Article
- Developmental and transcriptional responses to host and nonhost cuticles by the specific locust pathogen Metarhizium anisopliae var. acridum.Eukaryotic cell · 2005Article
- Fatal attraction: nonself recognition and heterokaryon incompatibility in filamentous fungi.Eukaryotic cell · 2003Review
- Identification of vib-1, a locus involved in vegetative incompatibility mediated by het-c in Neurospora crassa.Genetics · 2002Article
- Genomic evidence for a complete sexual cycle in Candida albicans.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Molecular genetics of heterokaryon incompatibility in filamentous ascomycetes.Microbiology and molecular biology reviews : MMBR · 2000Review
- MOD-D, a Galpha subunit of the fungus Podospora anserina, is involved in both regulation of development and vegetative incompatibility.Genetics · 1999Article
- Molecular characterization of tol, a mediator of mating-type-associated vegetative incompatibility in Neurospora crassa.Genetics · 1999Article
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Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vegetative incompatibility is widespread in fungi but its molecular mechanism and biological function are still poorly understood. A way to study vegetative incompatibility is to investigate the function of genes whose mutations suppress this phenomenon. In Podospora anserina, these genes are known as mod genes. In addition to suppressing vegetative incompatibility, mod mutations cause some developmental defects. This suggests that the molecular mechanisms of vegetative incompatibility and development pathway are interconnected. The mod-E1 mutation was isolated as a suppressor of the developmental defects of the mod-D2 strain. We show here that mod-E1 also partially suppresses vegetative incompatibility, strengthening the link between development and vegetative incompatibility. mod-E1 is the first suppressor of vegetative incompatibility characterized at the molecular level. It encodes a member of the Hsp90 family, suggesting that development and vegetative incompatibility use common steps of a signal transduction pathway. The involvement of mod-E in the sexual cycle has also been further investigated.
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