ArticleThe Journal of cell biology1997
The yeast motor protein, Kar3p, is essential for meiosis I.
Article in The Journal of cell biology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- Evidence of kinesin motors involved in stable kinetochore assembly during early meiosis.Molecular biology of the cell · 2023Article
- A grazing-driven positive nutrient feedback loop and active sexual reproduction underpin widespread Noctiluca green tides.ISME communications · 2022Article
- Meiosis-Specific Functions of Kinesin Motors in Cohesin Removal and Maintenance of Chromosome Integrity in Budding Yeast.Molecular and cellular biology · 2020Article
- Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission.PLoS pathogens · 2019Article
- The novel protein KBP regulates mitochondria localization by interaction with a kinesin-like protein.BMC cell biology · 2005Article
- Cik1 targets the minus-end kinesin depolymerase kar3 to microtubule plus ends.Current biology : CB · 2005Article
- The Drosophila meiotic mutant mei-352 is an allele of klp3A and reveals a role for a kinesin-like protein in crossover distribution.Genetics · 2005Article
- Novel response to microtubule perturbation in meiosis.Molecular and cellular biology · 2005Article
- Mechanistic analysis of the Saccharomyces cerevisiae kinesin Kar3.The Journal of biological chemistry · 2004Article
- Directed motion of telomeres in the formation of the meiotic bouquet revealed by time course and simulation analysis.Molecular biology of the cell · 2003Article
- The Kar3-interacting protein Cik1p plays a critical role in passage through meiosis I in Saccharomyces cerevisiae.Genetics · 2001Article
- Meiotic telomere protein Ndj1p is required for meiosis-specific telomere distribution, bouquet formation and efficient homologue pairing.The Journal of cell biology · 2000Article
- Article
- The Saccharomyces cerevisiae centromere protein Slk19p is required for two successive divisions during meiosis.Genetics · 2000Article
- Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis.Molecular and cellular biology · 1999Article
- A cytoplasmic dynein heavy chain is required for oscillatory nuclear movement of meiotic prophase and efficient meiotic recombination in fission yeast.The Journal of cell biology · 1999Article
- Differential regulation of the Kar3p kinesin-related protein by two associated proteins, Cik1p and Vik1p.The Journal of cell biology · 1999Article
- Telomere-mediated chromosome pairing during meiosis in budding yeast.Genes & development · 1998Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The recognition and alignment of homologous chromosomes early in meiosis is essential for their subsequent segregation at anaphase I; however, the mechanism by which this occurs is unknown. We demonstrate here that, in the absence of the molecular motor, Kar3p, meiotic cells are blocked with prophase monopolar microtubule arrays and incomplete synaptonemal complex (SC) formation. kar3 mutants exhibit very low levels of heteroallelic recombination. kar3 mutants do produce double-strand breaks that act as initiation sites for meiotic recombination in yeast, but at levels severalfold reduced from wild-type. These data are consistent with a meiotic role for Kar3p in the events that culminate in synapsis of homologues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.