Evidence map›Paper›PMID 9333064›Full record

ArticleAntimicrobial agents and chemotherapy1997

Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica.

S Ankri, T Miron, A Rabinkov, M Wilchek, D Mirelman

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 173 citations in OpenAlex.

  1. Interstellar Ice Chemistry Yields Elusive Sulfinothioic Acid (HS(O)SH).Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Allicin: a promising modulator of apoptosis and survival signaling in cancer.Medical oncology (Northwood, London, England) · 2024
    Review
  3. Impact of Reactive Sulfur Species onAntioxidants (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Garlic extract in prosthesis-related infections: a literature review.The Journal of international medical research · 2020
    Review
  9. Anti-biofilm activity of garlic extract loaded nanoparticles.Nanomedicine : nanotechnology, biology, and medicine · 2019
    Article
  10. Article
  11. Article
  12. Activity of Thioallyl Compounds From Garlic AgainstFrontiers in cellular and infection microbiology · 2018
    Article
  13. In Vitro and In Vivo Control of Secondary Bacterial Infection Caused by Leishmania major.International journal of environmental research and public health · 2017
    Article
  14. Antileishmanial and Immunomodulatory Activity of Allium sativum (Garlic): A Review.Journal of evidence-based complementary & alternative medicine · 2017
    Review
  15. Article
  16. Recent advances inF1000Research · 2016
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

S AnkriDepartment of Membrane Research and Biophysics, The Weizmann Institute of Science, Rehovot, Israel.
T Miron
A Rabinkov
M Wilchek
D Mirelman
Weizmann Institute of Science · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of Entamoeba histolytica trophozoites to destroy monolayers of baby hamster kidney cells is inhibited by allicin, one of the active principles of garlic. Cysteine proteinases, an important contributor to amebic virulence, as well as alcohol dehydrogenase, are strongly inhibited by allicin.

Indexed as

Plants, MedicinalAlcohol DehydrogenaseAnimalsAnti-Infective AgentsCells, CulturedCell SurvivalCricetinaeCysteine Proteinase InhibitorsDisulfidesEntamoeba histolyticaEntamoebiasisGarlicKineticsMicrobial Sensitivity TestsSulfinic AcidsAlcohol DehydrogenaseallicinAnti-Infective AgentsCysteine Proteinase InhibitorsDisulfidesSulfinic Acids

Identifiers

PMID9333064
PMCPMC164109
OpenAlexW2154918465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.