ArticleProceedings of the National Academy of Sciences of the United States of America1997
The heme oxygenase gene (pbsA) in the red alga Rhodella violacea is discontinuous and transcriptionally activated during iron limitation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 64 citations in OpenAlex.
- Plastid genome structure and phylogenomics of the freshwater red algal order Batrachospermales (Rhodophyta).Journal of phycology · 2026Article
- Article
- Plastid genome analysis of three Nemaliophycidae red algal species suggests environmental adaptation for iron limited habitats.PloS one · 2018Article
- The Transcriptional Landscape of the Photosynthetic Model Cyanobacterium Synechocystis sp. PCC6803.Scientific reports · 2016Article
- Article
- Scalable production of biliverdin IXα by Escherichia coli.BMC biotechnology · 2012Article
- Regulation of tomato lateral root development by carbon monoxide and involvement in auxin and nitric oxide.Journal of experimental botany · 2008Article
- Heme oxygenase up-regulation in ultraviolet-B irradiated soybean plants involves reactive oxygen species.Planta · 2006Article
- Expression and biochemical properties of a ferredoxin-dependent heme oxygenase required for phytochrome chromophore synthesis.Plant physiology · 2002Article
- The heme-oxygenase family required for phytochrome chromophore biosynthesis is necessary for proper photomorphogenesis in higher plants.Plant physiology · 2001Article
- Nitrogen or sulfur starvation differentially affects phycobilisome degradation and expression of the nblA gene in Synechocystis strain PCC 6803.Journal of bacteriology · 2001Article
- Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms.The Plant cell · 2001Article
- The photosynthetic apparatus of Prochlorococcus: Insights through comparative genomics.Photosynthesis research · 2001Article
- Effect of Bradyrhizobium photosynthesis on stem nodulation of Aeschynomene sensitiva.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- Kinetics of photoacclimation in response to a shift to high light of the red alga Rhodella violacea adapted to low irradiance.Plant physiology · 2000Article
- Use of heme compounds as iron sources by pathogenic neisseriae requires the product of the hemO gene.Journal of bacteriology · 2000Article
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2 authors at 1 institution in 1 country.
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Abstract
Heme oxygenase (HO) catalyzes the opening of the heme ring with the release of iron in both plants and animals. In cyanobacteria, red algae, and cryptophyceae, HO is a key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae. In an attempt to study the regulation of this key metabolic step, we cloned and sequenced the pbsA gene encoding this enzyme from the red alga Rhodella violacea. The gene is located on the chloroplast genome, split into three distant exons, and is presumably expressed by a trans-splicing mechanism. The deduced polypeptide sequence is homologous to other reported HOs from organisms containing phycobilisomes (Porphyra purpurea and Synechocystis sp. strain PCC 6803) and, to a lesser extent, to vertebrate enzymes. The expression is transcriptionally activated under iron deprivation, a stress condition frequently encountered by algae, suggesting a second role for HO as an iron-mobilizing agent in photosynthetic organisms.
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