Evidence map›Paper›PMID 9326336›Full record

ArticleAmerican journal of human genetics1997

Multilocus genotypes, a tree of individuals, and human evolutionary history.

J L Mountain, L L Cavalli-Sforza

Abstract read
In one paragraph

Article in American journal of human genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Article
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  14. Implications of the apportionment of human genetic diversity for the apportionment of human phenotypic diversity.Studies in history and philosophy of biological and biomedical sciences · 2015
    Article
  15. Article
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  18. Advancing genomic research and reducing health disparities: what can nurse scholars do?Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2013
    Article
  19. The behavior of admixed populations in neighbor-joining inference of population trees.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2013
    Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

J L MountainDepartment of Integrative Biology, University of California, Berkeley 94720-3140, USA. joanna@mws4.biol.berkeley.edu
L L Cavalli-Sforza

Funding

MODELS OF COMPLEX GENETIC SYSTEMSR01GM040282 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI SLATKIN, MONTGOMERY WILSON · 1988 to 2017
$4.4M
HUMAN POPULATION GENETICSR01GM020467 · NIGMS · STANFORD UNIVERSITY · PI CAVALLI-SFORZA, LUIGI L · 1985 to 1994
–
NIGMS NIH HHS GM20467NIGMS NIH HHS GM40282
6 · The paper itself

Abstract

Our goal is to infer, from human genetic data, general patterns as well as details of human evolutionary history. Here we present the results of an analysis of genetic data at the level of the individual. A tree relating 144 individuals from 12 human groups of Africa, Asia, Europe, and Oceania, inferred from an average of 75 DNA polymorphisms/individual, is remarkable in that most individuals cluster with other members of their regional group. In order to interpret this tree, we consider the factors that influence the tree pattern, including the number of genetic loci examined, the length of population isolation, the sampling process, and the extent of gene flow among groups. Understanding the impact of these factors enables us to infer details of human evolutionary history that might otherwise remain undetected. Our analyses indicate that some recent ancestor(s) of each of a few of the individuals tested may have immigrated. In general, the populations within regional groups appear to have been isolated from one another for <25,000 years. Regional groups may have been isolated for somewhat longer.

Indexed as

Biological EvolutionGenotypePhylogenyComputer SimulationDNAEmigration and ImmigrationGenetic MarkersHumansMutagenesisPolymorphism, Restriction Fragment LengthRacial GroupsDNAGenetic Markers

Identifiers

PMID9326336
PMCPMC1715971

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.