Evidence map›Paper›PMID 9324272›Full record

ArticleJournal of bacteriology1997

The major sigma factor (RpoD) from Helicobacter pylori and other gram-negative bacteria shows an enhanced rate of divergence.

J V Solnick, L M Hansen, M Syvanen

Abstract readComparative Study
In one paragraph

Article in Journal of bacteriology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Identification of candidate nucleomodulins in ESKAPE bacteria -Frontiers in cellular and infection microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J V SolnickDepartment of Internal Medicine, School of Medicine, University of California, Davis 95616, USA. jvsolnick@ucdavis.edu
L M Hansen
M Syvanen

Funding

REGULATION OF VIRULENCE GENES IN HELICOBACTER PYLORIK08AI001399 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI SOLNICK, JAY V. · 1996 to 1997
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NIAID NIH HHS 1K08AI01399-01
6 · The paper itself

Abstract

Sequence analysis of the Helicobacter pylori major sigma factor (RpoD) shows that it is highly divergent, which may be related to the marked diversity of the H. pylori chromosome. Furthermore, the rate of divergence of RpoD among other gram-negative bacteria is much greater than that among gram-positive bacteria. This suggests that RpoD from gram-negative bacteria is functionally less constrained than that from gram-positive bacteria.

Indexed as

Evolution, MolecularAmino Acid SequenceBacterial ProteinsBase SequenceChromosomes, BacterialDNA-Directed RNA PolymerasesGenetic VariationGram-Negative BacteriaGram-Positive BacteriaHelicobacter pyloriMolecular Sequence DataPhylogenySigma FactorBacterial ProteinsDNA-Directed RNA PolymerasesRNA polymerase sigma 70Sigma Factor

Identifiers

PMID9324272
PMCPMC179528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.