ArticleJournal of bacteriology1997
Homing of a group II intron from Lactococcus lactis subsp. lactis ML3.
Article in Journal of bacteriology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Methylation of rRNA as a host defense against rampant group II intron retrotransposition.Mobile DNA · 2021Article
- Recent horizontal transfer, functional adaptation and dissemination of a bacterial group II intron.BMC evolutionary biology · 2016Article
- Mobile Bacterial Group II Introns at the Crux of Eukaryotic Evolution.Microbiology spectrum · 2015Review
- Group II intron-ribosome association protects intron RNA from degradation.RNA (New York, N.Y.) · 2013Article
- Genetic and biochemical assays reveal a key role for replication restart proteins in group II intron retrohoming.PLoS genetics · 2013Article
- High efficiency recombineering in lactic acid bacteria.Nucleic acids research · 2012Article
- Global regulators orchestrate group II intron retromobility.Molecular cell · 2009Article
- The take and give between retrotransposable elements and their hosts.Annual review of genetics · 2008Review
- Trans-splicing of the Ll.LtrB group II intron in Lactococcus lactis.Nucleic acids research · 2007Article
- Restriction for gene insertion within the Lactococcus lactis Ll.LtrB group II intron.RNA (New York, N.Y.) · 2006Article
- Multicopy integration of heterologous genes, using the lactococcal group II intron targeted to bacterial insertion sequences.Applied and environmental microbiology · 2006Article
- Recruitment of host functions suggests a repair pathway for late steps in group II intron retrohoming.Genes & development · 2005Article
- Conjugative transfer of the Lactococcus lactis chromosomal sex factor promotes dissemination of the Ll.LtrB group II intron.Journal of bacteriology · 2005Article
- Gene targeting using randomly inserted group II introns (targetrons) recovered from an Escherichia coli gene disruption library.Nucleic acids research · 2005Article
- Localization, mobility and fidelity of retrotransposed Group II introns in rRNA genes.Nucleic acids research · 2005Article
- Conserved target for group II intron insertion in relaxase genes of conjugative elements of gram-positive bacteria.Journal of bacteriology · 2004Article
- A bacterial group II intron favors retrotransposition into plasmid targets.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Highly conjugative pMG1-like plasmids carrying Tn1546-like transposons that encode vancomycin resistance in Enterococcus faecium.Journal of bacteriology · 2003Article
- Diversity of group II introns in the genome of Sinorhizobium meliloti strain 1021: splicing and mobility of RmInt1.Molecular genetics and genomics : MGG · 2003Article
- The dispersal of five group II introns among natural populations of Escherichia coli.RNA (New York, N.Y.) · 2002Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ll.ltrB is a functional group II intron located within a gene (ltrB) encoding a conjugative relaxase essential for transfer of the lactococcal element pRSO1. In this work, the Ll.ltrB intron was shown to be an independent mobile element capable of inserting into an intronless allele of the ltrB gene. Ll.ltrB was not observed to insert into a deletion derivative of the ltrB gene in which the intron splice site was removed. In contrast, a second vector containing a 271-nucleotide segment of ltrB spanning the Ll.ltrB splice site was shown to be a proficient recipient of intron insertion. Efficient homing was observed in the absence of a functional host homologous recombination system. This work demonstrates that the Ll.ltrB intron is a novel site-specific mobile element in lactococci and that group II intron self-transfer is a mechanism for intron dissemination among bacteria.
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