ArticleJournal of medical genetics1997
Oculocutaneous albinism in an isolated Tonga community in Zimbabwe.
Article in Journal of medical genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Determining a Worldwide Prevalence of Oculocutaneous Albinism: A Systematic Review.Investigative ophthalmology & visual science · 2023Pooled it
- Albinism research in a Southern African setting: unique findings.Journal of community genetics · 2025Review
- The Impact of Oxytocin on Stimulus Discrimination of Zebrafish Albino and Non-Albino Models.International journal of molecular sciences · 2025Article
- Oculocutaneous albinism in southern Africa: Historical background, genetic, clinical and psychosocial issues.African journal of disability · 2022Article
- Towards an appropriate African framework for public engagement with human genome editing: a call to synergistic action.Wellcome open research · 2022Article
- Was skin cancer a selective force for black pigmentation in early hominin evolution?Proceedings. Biological sciences · 2014Review
- Histological review of skin cancers in African Albinos: a 10-year retrospective review.BMC cancer · 2014Review
- Two cases of burns in children from French Guinea with oculocutaneous albinism.Annals of burns and fire disasters · 2010Article
- Albinism in Africa as a public health issue.BMC public health · 2006Article
- Albinism: epidemiology, genetics, cutaneous characterization, psychosocial factors.Anais brasileiros de dermatologiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oculocutaneous albinism (OCA) is a recessively inherited genetic condition prevalent throughout sub-Saharan Africa. We now describe a cluster of tyrosinase positive OCA (OCA2) cases belonging to the Tonga ethnic group living in the Zambezi valley of northern Zimbabwe. The prevalence in this region was 1 in 1000, which is four times higher than that for the country as a whole. The gene frequency for OCA2 in this population was calculated as 0.0316, with a carrier rate of 1 in 16. Molecular analysis showed that all five affected subjects from two independent families examined were found to be homozygous for an interstitial 2.7 kb deletion mutation commonly found in OCA2 subjects in Africa. An obligate carrier from another family was heterozygous for this deletion allele. Affected subjects in this isolated community suffered health, social, and economic problems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.