ArticleNucleic acids research1997
Tc7, a Tc1-hitch hiking transposon in Caenorhabditis elegans.
Article in Nucleic acids research, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Article
- Visualization and Quantification of Transposon Activity inG3 (Bethesda, Md.) · 2019Article
- Genomic landscape and evolutionary dynamics of mariner transposable elements within the Drosophila genus.BMC genomics · 2014Article
- Forward and reverse mutagenesis in C. elegans.WormBook : the online review of C. elegans biology · 2014Review
- Transposable elements and the evolution of regulatory networks.Nature reviews. Genetics · 2008Review
- Structure and transcriptional impact of divergent repetitive elements inserted within Phanerochaete chrysosporium strain RP-78 genes.Molecular genetics and genomics : MGG · 2007Article
- Transposition of a fungal miniature inverted-repeat transposable element through the action of a Tc1-like transposase.Genetics · 2007Article
- The Caenorhabditis briggsae genome contains active CbmaT1 and Tcb1 transposons.Molecular genetics and genomics : MGG · 2005Article
- Article
- Continuous exchange of sequence information between dispersed Tc1 transposons in the Caenorhabditis elegans genome.Genetics · 2003Article
- Article
- Tc8, a Tourist-like transposon in Caenorhabditis elegans.Genetics · 2001Article
- Transposons but not retrotransposons are located preferentially in regions of high recombination rate in Caenorhabditis elegans.Genetics · 2000Article
- Repetitive-DNA elements are similarly distributed on Caenorhabditis elegans autosomes.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
We have found a novel transposon in the genome of Caenorhabditis elegans. Tc7 is a 921 bp element, made up of two 345 bp inverted repeats separated by a unique, internal sequence. Tc7 does not contain an open reading frame. The outer 38 bp of the inverted repeat show 36 matches with the outer 38 bp of Tc1. This region of Tc1 contains the Tc1-transposase binding site. Furthermore, Tc7 is flanked by TA dinucleotides, just like Tc1, which presumably correspond to the target duplication generated upon integration. Since Tc7 does not encode its own transposase but contains the Tc1-transposase binding site at its extremities, we tested the ability of Tc7 to jump upon forced expression of Tc1 transposase in somatic cells. Under these conditions Tc7 jumps at a frequency similar to Tc1. The target site choice of Tc7 is identical to that of Tc1. These data suggest that Tc7 shares with Tc1 all the sequences minimally required to parasitize upon the Tc1 transposition machinery. The genomic distribution of Tc7 shows a striking clustering on the X chromosome where two thirds of the elements (20 out of 33) are located. Related transposons in C. elegans do not show this asymmetric distribution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.