ArticleInfection and immunity1997
Enterococcus faecalis antigens in human infections.
Article in Infection and immunity, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 74 citations in OpenAlex.
- Insights into ecology, pathogenesis, and biofilm formation ofMicrobiology and molecular biology reviews : MMBR · 2025Review
- Current Knowledge of Enterococcal Endocarditis: A Disease Lurking in Plain Sight of Health Providers.Pathogens (Basel, Switzerland) · 2024Review
- Enterococcal Endocarditis: Hiding in Plain Sight.Frontiers in cellular and infection microbiology · 2021Review
- Cell wall polysaccharides of Gram positive ovococcoid bacteria and their role as bacteriophage receptors.Computational and structural biotechnology journal · 2021Review
- Article
- Extracellular SalB Contributes to Intrinsic Cephalosporin Resistance and Cell Envelope Integrity in Enterococcus faecalis.Journal of bacteriology · 2017Article
- Article
- Article
- EfaR is a major regulator of Enterococcus faecalis manganese transporters and influences processes involved in host colonization and infection.Infection and immunity · 2013Article
- The rise of the Enterococcus: beyond vancomycin resistance.Nature reviews. Microbiology · 2012Review
- The transcriptome of the nosocomial pathogen Enterococcus faecalis V583 reveals adaptive responses to growth in blood.PloS one · 2009Article
- Further characterization of the epa gene cluster and Epa polysaccharides of Enterococcus faecalis.Infection and immunity · 2009Article
- Contribution of the collagen adhesin Acm to pathogenesis of Enterococcus faecium in experimental endocarditis.Infection and immunity · 2008Article
- New insights into the Enterococcus faecalis CroRS two-component system obtained using a differential-display random arbitrarily primed PCR approach.Applied and environmental microbiology · 2007Article
- Native microbial colonization of Drosophila melanogaster and its use as a model of Enterococcus faecalis pathogenesis.Infection and immunity · 2007Article
- Opsonic antibodies to Enterococcus faecalis strain 12030 are directed against lipoteichoic acid.Infection and immunity · 2006Article
- Successful selection of cross-protective vaccine candidates for Ornithobacterium rhinotracheale infection.Infection and immunity · 2005Article
- Naturally acquired antibodies against four Enterococcus faecalis capsular polysaccharides in healthy human sera.Clinical and diagnostic laboratory immunology · 2005Article
- Differences in the Enterococcus faecalis lsa locus that influence susceptibility to quinupristin-dalfopristin and clindamycin.Antimicrobial agents and chemotherapy · 2005Article
- Mode of binding of fibrinogen, fibronectin and iron-binding proteins by animal enterococci.Veterinary research communications · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Genomic libraries of two Enterococcus faecalis strains, OG1RF and TX52 (an isolate from an endocarditis patient), were constructed in cosmid vectors pBeloBAC11 and pLAFRx, and screened with a serum from a rabbit immunized with surface proteins of an E. faecalis endocarditis isolate and sera from four patients with enterococcal endocarditis. Seventy-five cosmid clones reacted with at least two of the sera. Thirty-eight of the 75 immunopositive clones were considered to contain distinct inserts based on their DNA restriction patterns and were chosen for further subcloning into a pBluescript vector. Each sublibrary was screened with one of the five sera, and the DNA sequence of the immunopositive subclones was determined. Analysis of these sequences revealed similarities to a range of proteins, including bacterial virulence factors, transporters, two-component regulators, metabolic enzymes, and membrane or cell surface proteins. Fourteen subclones did not show significant similarity to any sequence in the databases and may contain novel genes. Thirteen of the immunopositive cosmid clones did not yield immunopositive subclones, and one such cosmid clone produced a nonprotein antigen in Escherichia coli.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.