ArticleJournal of virology1997
The transactivation domain of adenovirus E1A interacts with the C terminus of human TAF(II)135.
Article in Journal of virology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 51 citations in OpenAlex.
- Article
- Article
- Viral retasking of hBre1/RNF20 to recruit hPaf1 for transcriptional activation.PLoS pathogens · 2013Article
- Article
- Distinct modes of gene regulation by a cell-specific transcriptional activator.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP.Nucleic acids research · 2009Article
- Conditionally replicating adenoviruses for cancer treatment.Current cancer drug targets · 2007Review
- Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcription.The EMBO journal · 2006Article
- Tat gets the "green" light on transcription initiation.Retrovirology · 2005Review
- Article
- A novel tetracycline-controlled transactivator-transrepressor system enables external control of oncolytic adenovirus replication.Gene therapy · 2003Article
- Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB.Molecular and cellular biology · 2001Article
- Human Taf(II)130 is a coactivator for NFATp.Molecular and cellular biology · 2001Article
- Activation of the Notch-regulated transcription factor CBF1/RBP-Jkappa through the 13SE1A oncoprotein.Genes & development · 2001Article
- The human TFIID components TAF(II)135 and TAF(II)20 and the yeast SAGA components ADA1 and TAF(II)68 heterodimerize to form histone-like pairs.Molecular and cellular biology · 2000Article
- The activation domain of herpesvirus saimiri R protein interacts with the TATA-binding protein.Journal of virology · 1999Article
- Human TAF(II)55 interacts with the vitamin D(3) and thyroid hormone receptors and with derivatives of the retinoid X receptor that have altered transactivation properties.Molecular and cellular biology · 1999Article
- Synergistic transcriptional activation by TATA-binding protein and hTAFII28 requires specific amino acids of the hTAFII28 histone fold.Molecular and cellular biology · 1999Article
- Distinct subdomains of human TAFII130 are required for interactions with glutamine-rich transcriptional activators.Molecular and cellular biology · 1998Article
- Mouse adenovirus type 1 early region 1A is dispensable for growth in cultured fibroblasts.Journal of virology · 1998Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The CR3 activation domain of the human adenovirus E1A protein stimulates transcription by forming protein-protein interactions with DNA sequence-specific binding factors and components of the TFIID complex. Here, we demonstrate that CR3 can complex with the extreme C-terminal 105 amino acids of the human TATA box binding-factor-associated protein, hTAF(II)135. Furthermore, the C-terminal region of hTAF(II)135 can block transcriptional stimulation from an E1A-inducible promoter in vivo. This ability of the C terminus of hTAF(II)135 to bind CR3 and to inhibit E1A-inducible activation is highly specific. These results demonstrate for the first time that a discrete fragment of a mammalian TBP-associated factor which targets a specific activator can impair the stimulation of transcription.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.