ArticleJournal of virology1997
Foot-and-mouth disease virus and poliovirus particles contain proteins of the replication complex.
Article in Journal of virology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 33 citations in OpenAlex.
- Encapsidation of Viral RNA inJournal of virology · 2019Article
- Ammonia as an In Situ Sanitizer: Influence of Virus Genome Type on Inactivation.Applied and environmental microbiology · 2016Article
- The Rhinovirus subviral a-particle exposes 3'-terminal sequences of its genomic RNA.Journal of virology · 2014Article
- A safe foot-and-mouth disease vaccine platform with two negative markers for differentiating infected from vaccinated animals.Journal of virology · 2012Article
- Analysis of synonymous codon usage in foot-and-mouth disease virus.Veterinary research communications · 2010Article
- Functional analysis of picornavirus 2B proteins: effects on calcium homeostasis and intracellular protein trafficking.Journal of virology · 2008Article
- Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro.Virology journal · 2005Article
- Epitope mapping porcine reproductive and respiratory syndrome virus by phage display: the nsp2 fragment of the replicase polyprotein contains a cluster of B-cell epitopes.Journal of virology · 2001Article
- Processing of proteinase precursors and their effect on hepatitis A virus particle formation.Journal of virology · 1998Article
- Viral pollution in the environment and in shellfish: human adenovirus detection by PCR as an index of human viruses.Applied and environmental microbiology · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nonstructural proteins 2C, 3CD, 3C, and 3D, and the cellular protein actin, are present in highly purified preparations of foot-and-mouth disease virus (FMDV) and poliovirus. They remain bound in variable amounts to the RNAs when the RNAs are extracted from the viruses with phenol or phenol-sodium dodecyl sulfate (SDS) and, for FMDV, when the RNA is released from the particles by a lowering of the pH below 7. RNA prepared by these methods is rapidly degraded at 37 degrees C, particularly in the presence of NH4+ ions, but hydrolysis can be prevented by antibody against Escherichia coli-expressed 3D, indicating that it is the RNA polymerase that has nuclease activity. In contrast, virion RNA from which the nonstructural proteins and actin have been removed by extraction with guanidine thiocyanate-phenol-chloroform or proteinase K-phenol is stable at 37 degrees C, although its specific infectivity is lower than that of the RNA extracted with phenol or phenol-SDS. The possible implications of the close association of replication complex proteins with the RNA in virus particles are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.