ArticleGenes & development1997
Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog.
Article in Genes & development, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
99 citing papers in PubMed, 362 citations in OpenAlex.
- Ets2 Is an Activity-Dependent Transcriptional Regulator of a Fast-Twitch Muscle Program.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Gli3R-mediated inhibition of hedgehog signaling alters the embryonic transcriptome in zebrafish.G3 (Bethesda, Md.) · 2026Article
- An optimized in situ hybridization protocol to study early developmental patterns and signaling pathways in paradise fish (Macropodus opercularis).Biologia futura · 2026Article
- Location-Dependent Differences in Cardiac and Skeletal Muscle Dysfunction Associated With Truncating Titin (Circulation research · 2026Article
- The effects of temperature changes on Totoaba macdonaldi larval development, growth, and respiratory rates.Fish physiology and biochemistry · 2025Article
- Gli3R-mediated inhibition of hedgehog signaling alters the embryonic transcriptome in zebrafish.bioRxiv : the preprint server for biology · 2025Article
- Foxo3-mediated physiological cell competition ensures robust tissue patterning throughout vertebrate development.Nature communications · 2024Article
- The Pattern of Gene Expression (Animals : an open access journal from MDPI · 2024Article
- A Spatio-Temporal-Dependent Requirement of Sonic Hedgehog in the Early Development of Sclerotome-Derived Vertebrae and Ribs.International journal of molecular sciences · 2024Article
- Skeletal muscle regeneration after extensive cryoinjury of caudal myomeres in adult zebrafish.NPJ Regenerative medicine · 2024Article
- Slow myosin heavy chain 1 is required for slow myofibril and muscle fibre growth but not for myofibril initiation.Developmental biology · 2023Article
- Differentiation and Maturation of Muscle and Fat Cells in Cultivated Seafood: Lessons from Developmental Biology.Marine biotechnology (New York, N.Y.) · 2023Review
- Isolation, Culture, and Analysis of Zebrafish Myofibers and Associated Muscle Stem Cells to Explore Adult Skeletal Myogenesis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Loss of Myomixer Results in Defective Myoblast Fusion, Impaired Muscle Growth, and Severe Myopathy in Zebrafish.Marine biotechnology (New York, N.Y.) · 2022Article
- Somite morphogenesis is required for axial blood vessel formation during zebrafish embryogenesis.eLife · 2022Article
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- Mef2c factors are required for early but not late addition of cardiomyocytes to the ventricle.Developmental biology · 2021Article
- Myogenin is an essential regulator of adult myofibre growth and muscle stem cell homeostasis.eLife · 2020Article
- Fgf-driven Tbx protein activities directly induceDevelopment (Cambridge, England) · 2020Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The patterning of vertebrate somitic muscle is regulated by signals from neighboring tissues. We examined the generation of slow and fast muscle in zebrafish embryos and show that Sonic hedgehog (Shh) secreted from the notochord can induce slow muscle from medial cells of the somite. Slow muscle derives from medial adaxial myoblasts that differentiate early, whereas fast muscle arises later from a separate myoblast pool. Mutant fish lacking shh expression fail to form slow muscle but do form fast muscle. Ectopic expression of shh, either in wild-type or mutant embryos, leads to ectopic slow muscle at the expense of fast. We suggest that Shh acts to induce myoblasts committed to slow muscle differentiation from uncommitted presomitic mesoderm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.