ReviewMicrobiology and molecular biology reviews : MMBR1997
Microbial physiology and ecology of slow growth.
Review in Microbiology and molecular biology reviews : MMBR, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Global constraint principle for microbial growth laws.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A Multi-Omics, Machine Learning-Aware, Genome-Wide Metabolic Model of Bacillus Subtilis Refines the Gene Expression and Cell Growth Prediction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Genomic insights into redox-driven microbial processes for carbon decomposition in thawing Arctic soils and permafrost.mSphere · 2024Article
- Bio-organic fertilizers improveFrontiers in microbiology · 2023Article
- Construction and Analysis of an Enzyme-Constrained Metabolic Model ofBiomolecules · 2022Article
- Effects of Nutrient Level and Growth Rate on the Conjugation Process That Transfers Mobile Antibiotic Resistance Genes in Continuous Cultures.Applied and environmental microbiology · 2022Article
- Characterizing the Interplay of Rubisco and Nitrogenase Enzymes in Anaerobic-Photoheterotrophically Grown Rhodopseudomonas palustris CGA009 through a Genome-Scale Metabolic and Expression Model.Microbiology spectrum · 2022Article
- Article
- Bacterial chemotaxis to saccharides is governed by a trade-off between sensing and uptake.Biophysical journal · 2022Article
- ECMpy, a Simplified Workflow for Constructing Enzymatic Constrained Metabolic Network Model.Biomolecules · 2022Article
- Oligotrophy vs. copiotrophy in an alkaline and saline habitat of Lonar Lake.Frontiers in microbiology · 2022Article
- Article
- Article
- Pseudomonas aeruginosa displays a dormancy phenotype during long-term survival in water.PloS one · 2018Article
- Schrödinger's microbes: Tools for distinguishing the living from the dead in microbial ecosystems.Microbiome · 2017Review
- Competing metabolic strategies in a multilevel selection model.Royal Society open science · 2016Article
- The physiology of growth arrest: uniting molecular and environmental microbiology.Nature reviews. Microbiology · 2016Review
- Eradication ofFrontiers in microbiology · 2016Article
- Viruses Occur Incorporated in Biogenic High-Mg Calcite from Hypersaline Microbial Mats.PloS one · 2015Article
- Modeling adaptation of carbon use efficiency in microbial communities.Frontiers in microbiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The uptake capabilities of the cell have evolved to permit growth at very low external nutrient concentrations. How are these capabilities controlled when the substrate concentrations are not extremely low and the uptake systems could import substrate much more rapidly than the metabolic capabilities of the cell might be able to handle? To answer this question, earlier theories for the kinetics of uptake through the cell envelope and steady-state systems of metabolic enzymes are discussed and a computer simulation is presented. The problems to the cell of fluctuating levels of nutrient and too much substrate during continuous culture are discussed. Too much substrate can lead to oligotrophy, substrate-accelerated death, entry into the viable but not culturable state, and lactose killing. The relationship between uptake and growth is considered. Finally, too little substrate may lead to catastrophic attempts at mounting molecular syntheses that cannot be completed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.