ArticleGenetics1997
Evolutionary history of the sex-peptide (Acp70A) gene region in Drosophila melanogaster.
Article in Genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- The roles of gene duplications in the dynamics of evolutionary conflicts.Proceedings. Biological sciences · 2024Review
- Evolution of Reproductive Behavior.Genetics · 2020Review
- Chemical Cues that Guide Female Reproduction in Drosophila melanogaster.Journal of chemical ecology · 2018Review
- Roles of Female and Male Genotype in Post-Mating Responses in Drosophila melanogaster.The Journal of heredity · 2017Article
- Characterization of Reproductive Dormancy in MaleFrontiers in physiology · 2016Article
- Evolutionary rate covariation identifies new members of a protein network required for Drosophila melanogaster female post-mating responses.PLoS genetics · 2014Article
- The consequences of genetic variation in sex peptide expression levels for egg laying and retention in females.Heredity · 2012Article
- Molecular characterization and evolution of a gene family encoding male-specific reproductive proteins in the African malaria vector Anopheles gambiae.BMC evolutionary biology · 2011Article
- The genetic basis for male x female interactions underlying variation in reproductive phenotypes of Drosophila.Genetics · 2010Article
- Sperm proteomics reveals intensified selection on mouse sperm membrane and acrosome genes.Molecular biology and evolution · 2010Article
- Male accessory gland secretory protein polymorphism in natural populations of Drosophila nasuta nasuta and Drosophila sulfurigaster neonasuta.Journal of genetics · 2007Article
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- Unusual pattern of nucleotide sequence variation at the OS-E and OS-F genomic regions of Drosophila simulans.Genetics · 2007Article
- The evolutionary outcome of sexual conflict.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006Review
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- Article
- Article
- Sex peptide and the sperm effect in Drosophila melanogaster.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Article
- Applications of selective neutrality tests to molecular ecology.Molecular ecology · 2002Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Drosophila the products of the seminal fluid stimulate oviposition and suppress remating in the female. Of all the accessory gland peptides (Acp's) involved in these two responses, the sex-peptide (coded by the Acp70A gene) is among the best characterized at the functional level. A 1.2-kb fragment encompassing the Acp70A gene of nine lines from a natural population of D. melanogaster and one allele of D. sechellia was sequenced to study the forces shaping nucleotide variation within and between species. The coding region of D. simulans and D. mauritiana was also sequenced. A Ser to Ala replacement polymorphism at the last position of the signal peptide was detected in D. melanogaster. The Ser and Ala alleles are at intermediate frequencies. The level of nucleotide variation is lower for the derived Ala allele, which is compatible with a recent origin and an increase in frequency due to positive selection. Variation at the 5' flanking region is structured in two major highly differentiated haplotypes, whose distribution does not conform to neutral expectations. Selective and/or historical factors could contribute to the observed overall patterning of nucleotide variation at the Acp70A region.
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