ArticleInfection and immunity1997
Evidence for ethnic tropism of Helicobacter pylori.
Article in Infection and immunity, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 63 citations in OpenAlex.
- Echoes of a distant past: The cag pathogenicity island of Helicobacter pylori.Cold Spring Harbor perspectives in medicine · 2013Review
- Helicobacter pylori cagA status and peptic ulcer disease in Iran.Digestive diseases and sciences · 2009Article
- Urease activity and urea gene sequencing of coccoid forms of H. pylori induced by different factors.Current microbiology · 2008Article
- Clinical Relevance of the vacA, iceA, cagA, and flaA genes of Helicobacter pylori strains isolated in Eastern Taiwan.Journal of clinical microbiology · 2005Article
- Helicobacter pylori and gastroduodenal pathology: new threats of the old friend.Annals of clinical microbiology and antimicrobials · 2005Review
- High prevalence of multiple strain colonization of Helicobacter pylori in Korean patients: DNA diversity among clinical isolates from the gastric corpus, antrum and duodenum.The Korean journal of internal medicine · 2004Article
- Genotypes of Helicobacter pylori in patients with peptic ulcer bleeding.World journal of gastroenterology · 2004Article
- Enzyme-linked immunosorbent assay for Helicobacter pylori needs adjustment for the population investigated.Journal of clinical microbiology · 2004Article
- Polymorphisms of Helicobacter pylori HP0638 reflect geographic origin and correlate with cagA status.Journal of clinical microbiology · 2002Article
- Phenotypic variation of Helicobacter pylori isolates from geographically distinct regions detected by lectin typing.Journal of clinical microbiology · 2002Article
- Helicobacter pylori: clonal population structure and restricted transmission within families revealed by molecular typing.Journal of clinical microbiology · 2000Article
- Differentiation of Helicobacter pylori isolates based on lectin binding of cell extracts in an agglutination assay.Journal of clinical microbiology · 1999Article
- Molecular characterization of a flagellar export locus of Helicobacter pylori.Infection and immunity · 1999Article
- Helicobacter pylori heat shock protein A: serologic responses and genetic diversity.Clinical and diagnostic laboratory immunology · 1999Article
- Development of a scheme for genotyping Helicobacter pylori based on allelic variation in urease subunit genes.Journal of clinical microbiology · 1998Article
- Population characteristics of Irish Helicobacter pylori isolates: a tRNA-associated locus.Irish journal of medical scienceArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori infection in humans is linked to gastritis, gastric and duodenal ulcers, and gastric cancer. Peptic ulcer disease, as distinct from chronic asymptomatic infection, is strongly associated with expression of bacterial virulence markers, including a major antigen, CagA, and the vacuolating cytotoxin VacA. We have previously described significant differences in colonization rates, independent of socioeconomic status, among ethnic groups in New Zealand. To evaluate relative risks for peptic ulcer disease, we examined the frequency of two virulence markers in H. pylori strains infecting these ethnic groups. Although these markers occurred significantly more frequently in strains isolated from Polynesians than in strains from Europeans, this frequency was not reflected in the incidence of peptic ulcer disease in the two groups. DNA fingerprinting of the urease gene showed that Polynesians are more frequently infected by a group of strains which are genetically distinct from those affecting European New Zealanders. Our data suggest that separate bacterial lineages may have evolved in parallel with race-specific specialization.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.