ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners1997
Aspirin use in middle-aged men with cardiovascular disease: are opportunities being missed?
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Effect of low-dose aspirin on health outcomes: An umbrella review of systematic reviews and meta-analyses.British journal of clinical pharmacology · 2020Pooled it
- Systematic review of studies of quality of clinical care in general practice in the UK, Australia and New Zealand.Quality in health care : QHC · 2001Pooled it
- Equity in the use of antithrombotic drugs, beta-blockers and statins among Finnish coronary patients.International journal for equity in health · 2008Article
- Secondary prevention of coronary heart disease in older British men: extent of inequalities before and after implementation of the National Service Framework.Journal of public health (Oxford, England) · 2005Article
- Why are eligible patients not prescribed aspirin in primary care? A qualitative study indicating measures for improvement.BMC family practice · 2003Article
- Use of statins in the secondary prevention of coronary heart disease: is treatment equitable?Heart (British Cardiac Society) · 2002Article
- Low prevalence of lipid lowering drug use in older men with established coronary heart disease.Heart (British Cardiac Society) · 2002Article
- Aspirin use for the prevention of cardiovascular disease: the British Women's Heart and Health Study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2001Article
- Identifying patients with ischaemic heart disease in general practice: cross sectional study of paper and computerised medical records.BMJ (Clinical research ed.) · 2000Article
- Secondary prevention in coronary heart disease. Cost effectiveness of treatment must be borne in mind.BMJ (Clinical research ed.) · 1998Article
- Platelets, aspirin, and cardiovascular disease.Postgraduate medical journal · 1998Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince the 1980s, clinical trial evidence has supported aspirin use in the secondary prevention of cardiovascular disease (CVD).
aimTo explore aspirin use among British men with known CVD in a population-based study.
methodLongitudinal study (British Regional Heart Study), in which subjects have been followed up for cardiovascular morbidity and mortality since 1978-1980. Aspirin use was assessed by questionnaires to study participants in November 1992 (Q92); cardiovascular diagnoses are based on general practice notifications to October 1992. A total of 5751 men aged 52-73 years (87% of survivors) completed questions on aspirin use.
resultsOverall, 547 men (9.5%) were taking aspirin daily, of whom 321 (59%) had documented CVD. Among men with pre-existing disease, 153 out of 345 (44%) men with myocardial infarction, 42 out of 109 (39%) with stroke, and 75 out of 247 (29%) with angina were taking aspirin daily. Among men with angina (54% versus 26%) or myocardial infarction (59% versus 42%), those who had undergone coronary artery bypass surgery (CABG) or angioplasty were more likely to be receiving aspirin. Higher rates of aspirin use were also found in those whose last major event occurred after January 1990 (47% versus 34%). There was no association between aspirin use and social class or region of residence.
conclusionDespite strong evidence of its effectiveness, many patients with established CVD were not receiving aspirin. Daily aspirin treatment was less likely in men with less recent major CVD events and in those who had not received invasive treatment.
Indexed as
Identifiers
9281867PMC1313050W1746446148What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.