ArticleNucleic acids research1997
Reduced RNA polymerase II transcription in extracts of cockayne syndrome and xeroderma pigmentosum/Cockayne syndrome cells.
Article in Nucleic acids research, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 81 citations in OpenAlex.
- Transcription-coupled repair: tangled up in convoluted repair.The FEBS journal · 2025Review
- Discovery of a new hereditary RECQ helicase disorder RECON syndrome positions the replication stress response and genome homeostasis as centrally important processes in aging and age-related disease.Ageing research reviews · 2023Review
- The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites.International journal of molecular sciences · 2021Article
- Current and emerging roles of Cockayne syndrome group B (CSB) protein.Nucleic acids research · 2021Review
- G-Quadruplex Assembly by Ribosomal DNA: Emerging Roles in Disease Pathogenesis and Cancer Biology.Cytogenetic and genome research · 2021Review
- Spironolactone-induced degradation of the TFIIH core complex XPB subunit suppresses NF-κB and AP-1 signalling.Cardiovascular research · 2018Article
- Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony.Human molecular genetics · 2016Article
- Regulation of active genome integrity and expression by Rad26p.Nucleus (Austin, Tex.) · 2014Review
- UVSSA and USP7, a new couple in transcription-coupled DNA repair.Chromosoma · 2013Review
- Regulatory interplay of Cockayne syndrome B ATPase and stress-response gene ATF3 following genotoxic stress.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair.Nature genetics · 2012Article
- TFIIH is an elongation factor of RNA polymerase I.Nucleic acids research · 2012Article
- DNA repair deficiency in neurodegeneration.Progress in neurobiology · 2011Review
- Article
- Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndrome.Molecular and cellular biology · 2007Article
- Cockayne syndrome B protein regulates the transcriptional program after UV irradiation.The EMBO journal · 2006Article
- Different effects of CSA and CSB deficiency on sensitivity to oxidative DNA damage.Molecular and cellular biology · 2004Article
- DNA damage stabilizes interaction of CSB with the transcription elongation machinery.The Journal of cell biology · 2004Article
- Article
- Subnuclear localization of Ku protein: functional association with RNA polymerase II elongation sites.Molecular and cellular biology · 2002Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hereditary disease Cockayne syndrome (CS) is a complex clinical syndrome characterized by arrested post-natal growth as well as neurological and other defects. The CSA and CSB genes are implicated in this disease. The clinical features of CS can also accompany the excision repair-defective hereditary disorder xeroderma pigmentosum (XP) from genetic complementation groups B, D or G. The XPB and XPD proteins are subunits of RNA polymerase II (RNAP II) transcription factor IIH (TFIIH). We show here that extracts of CS-A and CS-B cells, as well as those from XP-B/CS cells, support reduced levels of RNAP II transcription in vitro and that this feature is dependent on the state or quality of the template.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.