ReviewCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne1997
Primary prevention of heart disease and stroke: a simplified approach to estimating risk of events and making drug treatment decisions.
Review in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Framingham-based tools to calculate the global risk of coronary heart disease: a systematic review of tools for clinicians.Journal of general internal medicine · 2003Pooled it
- Using disease risk estimates to guide risk factor interventions: field test of a patient workbook for self-assessing coronary risk.Health expectations : an international journal of public participation in health care and health policy · 2002Article
- Comparative accuracy of cardiovascular risk prediction methods in primary care patients.Heart (British Cardiac Society) · 2001Article
- Patients offered treatment for CHD need full information to make decisionBMJ (Clinical research ed.) · 1998Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Long-term population-based studies have identified and quantified risk factors for cardiovascular and cerebrovascular (CCV) events. In addition, a number of well-designed clinical trials have shown that various drug therapies that reduce these factors decrease the risk of some CCV events. In the practice of evidence-based medicine, data from clinical trials should inform treatment decisions. The clinician and patient, however, are faced with the difficult task of assessing the patient's particular risk and likelihood of benefit on the basis of the results of large, randomized trials. To assist clinicians and their patients in arriving at treatment decisions, the authors provide simple nomograms for estimating the risk of a CCV event for an individual patient and suggest an approach to estimating the potential benefit of drug therapy for primary prevention.
Indexed as
Identifiers
9275953PMC1227917W1953940293What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.