Evidence map›Paper›PMID 9275698›Full record

ArticleJournal of Tongji Medical University = Tong ji yi ke da xue xue bao1996

Differentiation of osteoblast in vitro is regulated by progesterone.

L Chen, N T Foged

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Induction of osteocalcin gene expression in vitro by progesterone.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao · 1997
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

L ChenDepartment of Endocrinology, Xiehe Hospital, Tongji Medical University, Wuhan.
N T Foged
Center for Clinical & Basic Research · DKTongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regulation of cellular differentiation by progesterone in fetal rat calvarial osteoblasts was investigated. Our results showed that cells cultured in the presence of progesterone had a 7% increase in the alkaline phosphatase activity when compared to untreated cells. The concentration of osteocalcin in the conditioned medium from progesterone treated osteoblasts was 28% higher than that of untreated controls. In addition, administration of progesterone significantly enhanced the number and area of bone nodules. In conclusion, progesterone stimulates the differentiation of fetal rat calvarial osteoblastic cells in vitro.

Indexed as

Alkaline PhosphataseAnimalsCell DifferentiationCells, CulturedFetusOsteoblastsOsteocalcinProgesteroneRatsRats, Sprague-DawleySkullAlkaline PhosphataseOsteocalcinProgesterone

Identifiers

PMID9275698
OpenAlexW2053783868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.