ArticleJournal of autism and developmental disorders1997
Autistic behaviors among girls with fragile X syndrome.
Article in Journal of autism and developmental disorders, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- Psychiatric difficulties in females with fragile X syndrome: a systematic review and meta-analyses.Frontiers in psychiatry · 2026Pooled it
- Autism spectrum disorder in females with fragile X syndrome: a systematic review and meta-analysis of prevalence.Journal of neurodevelopmental disorders · 2021Pooled it
- Longitudinal Changes in Functional Neural Activation and Sensitization During Face Processing in Fragile X Syndrome.Biological psychiatry · 2025Article
- The Impact of Mild Chronic Stress and Maternal Experience in theInternational journal of molecular sciences · 2023Article
- Distinct social attention profiles in preschoolers with autism contrasted to fragile X syndrome.Autism research : official journal of the International Society for Autism Research · 2023Article
- Neuroanatomical Profile of Young Females with Fragile X Syndrome: A Voxel-Based Morphometry Analysis.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Autistic-like behavioral effects of prenatal stress in juvenile Fmr1 mice: the relevance of sex differences and gene-environment interactions.Scientific reports · 2022Article
- Empathy and Anxiety in Young Girls with Fragile X Syndrome.Journal of autism and developmental disorders · 2022Article
- Screening forBioMed research international · 2021Article
- Genetic Testing in Neurodevelopmental Disorders.Frontiers in pediatrics · 2021Review
- Child Challenging Behavior Influences Maternal Mental Health and Relationship Quality Over Time in Fragile X Syndrome.Journal of autism and developmental disorders · 2020Article
- Intellectual functioning and behavioural features associated with mosaicism in fragile X syndrome.Journal of neurodevelopmental disorders · 2019Article
- Significantly ElevatedInternational journal of molecular sciences · 2019Article
- Closing the Gender Gap in Fragile X Syndrome: Review on Females with FXS and Preliminary Research Findings.Brain sciences · 2019Review
- A Multimethod Analysis of Pragmatic Skills in Children and Adolescents With Fragile X Syndrome, Autism Spectrum Disorder, and Down Syndrome.Journal of speech, language, and hearing research : JSLHR · 2018Article
- Noncomprehension Signaling in Males and Females With Fragile X Syndrome.Journal of speech, language, and hearing research : JSLHR · 2017Article
- Molecular medicine of fragile X syndrome: based on known molecular mechanisms.World journal of pediatrics : WJP · 2016Review
- The Role of mGluR Copy Number Variation in Genetic and Environmental Forms of Syndromic Autism Spectrum Disorder.Scientific reports · 2016Article
- A developmental, longitudinal investigation of autism phenotypic profiles in fragile X syndrome.Journal of neurodevelopmental disorders · 2016Article
- Do Children With Fragile X Syndrome Show Declines or Plateaus in Adaptive Behavior?American journal on intellectual and developmental disabilities · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Reports of autistic behaviors were examined for 30 school-age girls with fragile X (fraX) and 31 age- and IQ-matched controls through a structured interview administered to each girl's parent(s). IQ scores were obtained for each participant; anxiety, neuroanatomical, and molecular-genetic data were derived for girls with fraX. Girls with fraX had significantly more autistic behaviors than controls. These behaviors were qualitatively similar to those reported for boys with fraX, but were not correlated with IQ. Anxiety in girls with fraX was positively correlated with abnormal social and communication behaviors; posterior cerebellar vermis area was negatively correlated with measures of communication and stereotypic/restricted behaviors. Severity of stereotypic/restricted behaviors was negatively correlated with the prevalence of active non-fraX chromosomes. Thus anxiety and posterior cerebellar area measures had distinct associations with subsets of autistic behaviors; these associations may have important implications for understanding the neurobiology of autism.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.