ArticleJournal of bacteriology1997
Colicin U, a novel colicin produced by Shigella boydii.
Article in Journal of bacteriology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 72 citations in OpenAlex.
- The "Cins" of Our Fathers: Rejuvenated Interest in Colicins to Combat Drug Resistance.Journal of microbiology (Seoul, Korea) · 2023Review
- Bacterial pore-forming toxins.Microbiology (Reading, England) · 2022Article
- Structural and functional insights into colicin: a new paradigm in drug discovery.Archives of microbiology · 2021Review
- Roles of OmpA in Type III Secretion System-Mediated Virulence of EnterohemorrhagicPathogens (Basel, Switzerland) · 2021Article
- Escherichia coli Strains Producing Selected Bacteriocins Inhibit Porcine Enterotoxigenic Escherichia coli (ETEC) under bothApplied and environmental microbiology · 2021Article
- The Evolution of Mass Cell Suicide in Bacterial Warfare.Current biology : CB · 2020Article
- Deciphering the Role of Colicins during Colonization of the Mammalian Gut by CommensalMicroorganisms · 2020Article
- Colicin U from Shigella boydii Forms Voltage-Dependent Pores.Journal of bacteriology · 2019Article
- Colicin Z, a structurally and functionally novel colicin type that selectively kills enteroinvasive Escherichia coli and Shigella strains.Scientific reports · 2019Article
- Partial Characterization of Novel Bacteriocin SF1 Produced byInternational journal of microbiology · 2019Article
- Similarities and Differences between Colicin and Filamentous Phage Uptake by Bacterial Cells.EcoSal Plus · 2019Review
- Colicin FScientific reports · 2018Article
- When pathogenic bacteria meet the intestinal microbiota.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Activity spectrum of colicins produced by Shigella sonnei and genetic mechanism of colicin resistance in conspecific S. sonnei strains and Escherichia coli.Antimicrobial agents and chemotherapy · 2015Article
- Article
- A new biofilm-associated colicin with increased efficiency against biofilm bacteria.The ISME journal · 2014Article
- Antibacterial activities of bacteriocins: application in foods and pharmaceuticals.Frontiers in microbiology · 2014Review
- Antagonistic activity expressed by Shigella sonnei: identification of a putative new bacteriocin.Memorias do Instituto Oswaldo Cruz · 2013Article
- Colicin type 7 produced by majority of Shigella sonnei isolated from Thai patients with diarrhoea.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2013Article
- Block and boost DNA transfer: opposite roles of OmpA in natural and artificial transformation of Escherichia coli.PloS one · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel colicin, designated colicin U, was found in two Shigella boydii strains of serovars 1 and 8. Colicin U was active against bacterial strains of the genera Escherichia and Shigella. Plasmid pColU (7.3 kb) of the colicinogenic strain S. boydii M592 (serovar 8) was sequenced, and three colicin genes were identified. The colicin U activity gene, cua, encodes a protein of 619 amino acids (Mr, 66,289); the immunity gene, cui, encodes a protein of 174 amino acids (Mr, 20,688); and the lytic protein gene, cul, encodes a polypeptide of 45 amino acids (Mr, 4,672). Colicin U displays sequence similarities to various colicins. The N-terminal sequence of 130 amino acids has 54% identity to the N-terminal sequence of bacteriocin 28b produced by Serratia marcescens. Furthermore, the N-terminal 36 amino acids have striking sequence identity (83%) to colicin A. Although the C-terminal pore-forming sequence of colicin U shows the highest degree of identity (73%) to the pore-forming C-terminal sequence of colicin B, the immunity protein, which interacts with the same region, displays a higher degree of sequence similarity to the immunity protein of colicin A (45%) than to the immunity protein of colicin B (30.5%). Immunity specificity is probably conferred by a short sequence from residues 571 to residue 599 of colicin U; this sequence is not similar to that of colicin B. We showed that binding of colicin U to sensitive cells is mediated by the OmpA protein, the OmpF porin, and core lipopolysaccharide. Uptake of colicin U was dependent on the TolA, -B, -Q, and -R proteins. pColU is homologous to plasmid pSB41 (4.1 kb) except for the colicin genes on pColU. pSB41 and pColU coexist in S. boydii strains and can be cotransformed into Escherichia coli, and both plasmids are homologous to pColE1.
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