Evidence map›Paper›PMID 9238111›Full record

ReviewPediatric surgery international1997

Cultured epithelial autografts: diving from surgery into matrix biology.

M Raghunath, M Meuli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric surgery international, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Long-Term Outcomes of a Cultured Autologous Dermo-Epidermal Skin Substitute in Children: 5-Year Results of a Phase I Clinical Trial.Journal of burn care & research : official publication of the American Burn Association · 2025
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  11. Tissue engineering of cultured skin substitutes.Journal of cellular and molecular medicine
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M RaghunathDepartment of Dermatology, University of Münster, Von-Esmarch-Strasse 56, D-48149 Münster, Germany.
M Meuli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cultured epithelial autografts offer an exciting approach to cover extensive skin wounds. The main problem of this method is mechanical instability during the first weeks after grafting. There is evidence that the shortcomings of autografting cultured keratinocytes result from the lack of a mature and functional dermo-epidermal junction. This article summarizes the current knowledge regarding the de novo formation of the dermo-epidermal junction and the dynamics of "take" and stabilization of cultured epithelial autografts. Future strategies are discussed of how to improve and accelerate the process conferring definitive stabilization of cultured epithelial autografts including the potential therapeutic use of transglutaminase as well as cocultivation of a dermo-epidermal equivalent in order to facilitate a permanent skin replacement.

Indexed as

GTP-Binding ProteinsSkin Physiological PhenomenaBurnsCells, CulturedEpidermal CellsEpithelial CellsEpitheliumFactor XIIIGTP PhosphohydrolasesHumansKeratinocytesProtein Glutamine gamma Glutamyltransferase 2RegenerationSkinSkin TransplantationTransglutaminasesFactor XIIIGTP-Binding ProteinsGTP PhosphohydrolasesProtein Glutamine gamma Glutamyltransferase 2Transglutaminases

Identifiers

PMID9238111

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.