ArticleAnalytical biochemistry1997
Lifetime-based sensing of glucose using energy transfer with a long lifetime donor.
Article in Analytical biochemistry, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.
- Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.Diabetes care · 2011Guideline
- Long-distance tmFRET using bipyridyl- and phenanthroline-based ligands.Biophysical journal · 2024Article
- Long-distance tmFRET using bipyridyl- and phenanthroline-based ligands.bioRxiv : the preprint server for biology · 2024Article
- Overcoming the aggregation problem: a new type of fluorescent ligand for ConA-based glucose sensing.Biosensors & bioelectronics · 2015Article
- Glucose sensors based on microcapsules containing an orange/red competitive binding resonance energy transfer assay.Diabetes technology & therapeutics · 2006Article
- Complexation of polysaccharide and monosaccharide with thiolate boronic acid capped on silver nanoparticle.Analytical biochemistry · 2004Article
- Protein-based biosensors for diabetic patients.Journal of fluorescence · 2004Article
- Time-resolved fluorescent imaging of glucose.Journal of fluorescence · 2004Article
- Glucose-sensitive nanoassemblies comprising affinity-binding complexes trapped in fuzzy microshells.Journal of fluorescence · 2004Article
- Fluorescence glucose detection: advances toward the ideal in vivo biosensor.Journal of fluorescence · 2004Review
- Aggregation of Silver Nanoparticle-Dextran Adducts with Concanavalin A and Competitive Complexation with Glucose.The journal of physical chemistry. B · 2004Article
- On the Possibility of Glucose Sensing Using Boronic Acid and a Luminescent Ruthenium Metal-Ligand Complex.Journal of fluorescence · 2002Article
- A novel fluorescence competitive assay for glucose determinations by using a thermostable glucokinase from the thermophilic microorganism Bacillus stearothermophilus.Analytical biochemistry · 2002Article
- In vivo glucose sensing for diabetes management: progress towards non-invasive monitoring. Interview by Judy Jones.BMJ (Clinical research ed.) · 1999Article
- The fluorescence emission of the apo-glucose oxidase from Aspergillus niger as probe to estimate glucose concentrations.Biochemical and biophysical research communications · 1999Article
- Resonance energy transfer study using a rhenium metal-ligand lipid conjugate as the donor in a model membrane.Chemistry and physics of lipids · 1999Article
- Glucose sensor for low-cost lifetime-based sensing using a genetically engineered protein.Analytical biochemistry · 1999Article
- Optical assay for glucose based on the luminescnence decay time of the long wavelength dye Cy5™.Sensors and actuators. B, Chemical · 1997Article
- Resonance energy transfer nanobiosensors based on affinity binding between apo-enzyme and its substrate.BiomacromoleculesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
We describe an optical assay for glucose based on the luminescence decay time of a long lifetime metal-ligand complex. Concanavalin A was covalently labeled with Ruthenium metal-ligand complex (RuCon A) which served as the donor. The acceptor was malachite green which was covalently linked to insulin. The malachite green insulin was also covalently labeled with maltose (MIMG) to provide binding affinity to RuCon A. Binding of RuCon A to MIMG resulted in a decreased intensity and decay time of RuCon A. Glucose was detected by competitive displacement of MIMG from RuCon A, resulting in increased intensity and decay time. This glucose assay has several favorable features. The long lifetime of RuCon A allows phase-modulation decay time measurements using an amplitude-modulated bluelight-emitting diode as the light source. Reversibility of the assay can be controlled by the extent of sugar labeling of the insulin. Finally, the glucose-sensitive range can be adjusted by selection of the sugar structure and extent of labeling of the insulin.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.