ArticleThe EMBO journal1997
A new gene encoding a putative transcription factor regulated by the Drosophila circadian clock.
Article in The EMBO journal, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- A transcription network underlies the dual genomic coordination of mitochondrial biogenesis.eLife · 2024Article
- A transcription network underlies the dual genomic coordination of mitochondrial biogenesis.bioRxiv : the preprint server for biology · 2024Article
- Article
- Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver.Cell metabolism · 2017Article
- Circadian organization of behavior and physiology in Drosophila.Annual review of physiology · 2010Review
- SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age-related neoplasms.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2009Review
- Duplicate gene evolution toward multiple fates at the Drosophila melanogaster HIP/HIP-Replacement locus.Journal of molecular evolution · 2009Article
- A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock.Genes & development · 2007Article
- Drosophila doubletime mutations which either shorten or lengthen the period of circadian rhythms decrease the protein kinase activity of casein kinase I.Molecular and cellular biology · 2004Article
- Genome-wide expression analysis in Drosophila reveals genes controlling circadian behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- takeout, a novel Drosophila gene under circadian clock transcriptional regulation.Molecular and cellular biology · 2000Article
- Ectopic expression of the neuropeptide pigment-dispersing factor alters behavioral rhythms in Drosophila melanogaster.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
- Differential regulation of circadian pacemaker output by separate clock genes in Drosophila.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- From biological clock to biological rhythms.Genome biology · 2000Review
- Article
- TIMELESS-dependent positive and negative autoregulation in the Drosophila circadian clock.The EMBO journal · 1999Article
- Circadian regulation of a Drosophila homolog of the mammalian Clock gene: PER and TIM function as positive regulators.Molecular and cellular biology · 1998Article
- Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Drosophila photoreceptors contain an autonomous circadian oscillator that can function without period mRNA cycling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1998Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circadian rhythms of locomotor activity and eclosion in Drosophila depend upon the reciprocal autoregulation of the period (per) and timeless (tim) genes. As part of this regulatory loop, per and tim mRNA levels oscillate in a circadian fashion. Other cycling transcripts may participate in this central pacemaker mechanism or represent outputs of the clock. In this paper, we report the isolation of Crg-1, a new circadianly regulated gene. Like per and tim transcript levels, Crg-1 transcript levels oscillate with a 24 h period in light:dark (LD) conditions, with a maximal abundance at the beginning of the night. These oscillations persist in complete darkness and depend upon per and tim proteins. The putative CRG-1 proteins show some sequence similarity with the DNA-binding domain of the HNF3/fork head family of transcription factors. In the adult head, in situ hybridization analysis reveals that per and Crg-1 have similar expression patterns in the eyes and optic lobes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.