ArticleJournal of bacteriology1997
A novel ribosome-associated protein is important for efficient translation in Escherichia coli.
Article in Journal of bacteriology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 49 citations in OpenAlex.
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- RNase-mediated reprogramming of Yersinia virulence.PLoS pathogens · 2024Article
- Comprehensive essentiality analysis of themBio · 2023Article
- Emerging Quantitative Biochemical, Structural, and Biophysical Methods for Studying Ribosome and Protein-RNA Complex Assembly.Biomolecules · 2023Review
- Protein Assistants of Small Ribosomal Subunit Biogenesis in Bacteria.Microorganisms · 2022Review
- Structural Basis for the C-Terminal Domain ofBiomolecules · 2021Article
- Characterization and Transcriptome Studies of Autoinducer Synthase Gene from Multidrug ResistantGenes · 2019Article
- Escherichia coli rimM and yjeQ null strains accumulate immature 30S subunits of similar structure and protein complement.RNA (New York, N.Y.) · 2013Article
- Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process.Nucleic acids research · 2013Article
- G-patch domain and KOW motifs-containing protein, GPKOW; a nuclear RNA-binding protein regulated by protein kinase A.Journal of molecular signaling · 2011Article
- Alterations in the β flap and β' dock domains of the RNA polymerase abolish NusA-mediated feedback regulation of the metY-nusA-infB operon.Journal of bacteriology · 2011Article
- The effect of ribosome assembly cofactors on in vitro 30S subunit reconstitution.Journal of molecular biology · 2010Article
- Appropriate maturation and folding of 16S rRNA during 30S subunit biogenesis are critical for translational fidelity.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Genetic interaction screens with ordered overexpression and deletion clone sets implicate the Escherichia coli GTPase YjeQ in late ribosome biogenesis.Journal of bacteriology · 2008Article
- Structural characterization of the ribosome maturation protein, RimM.Journal of bacteriology · 2007Article
- A sensor of the two-component system CpxA affects expression of the type III secretion system through posttranscriptional processing of InvE.Journal of bacteriology · 2005Article
- The PRC-barrel domain of the ribosome maturation protein RimM mediates binding to ribosomal protein S19 in the 30S ribosomal subunits.RNA (New York, N.Y.) · 2004Article
- Atypical 16S rRNA gene copies in Ochrobactrum intermedium strains reveal a large genomic rearrangement by recombination between rrn copies.Journal of bacteriology · 2003Article
- The PRC-barrel: a widespread, conserved domain shared by photosynthetic reaction center subunits and proteins of RNA metabolism.Genome biology · 2002Article
- Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities.The EMBO journal · 2002Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previously, we showed that strains which have been deleted for the 21K gene (hereafter called yfjA), of the trmD operon, encoding a 21-kDa protein (21K protein) have an approximately fivefold-reduced growth rate in rich medium. Here we show that such mutants show an up to sevenfold reduced growth rate in minimal medium, a twofold-lower cell yield-to-carbon source concentration ratio, and a reduced polypeptide chain growth rate of beta-galactosidase. Suppressor mutations that increased the growth rate and translational efficiency of a delta yfjA mutant were localized to the 3' part of rpsM, encoding ribosomal protein S13. The 21K protein was shown to have affinity for free 30S ribosomal subunits but not for 70S ribosomes. Further, the 21K protein seems to contain a KH domain and a KOW motif, both suggested to be involved in binding of RNA. These findings suggest that the 21K protein is essential for a proper function of the ribosome and is involved in the maturation of the ribosomal 30S subunits or in translation initiation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.