ArticleNucleic acids research1997
Representation of cloned genomic sequences in two sequencing vectors: correlation of DNA sequence and subclone distribution.
Article in Nucleic acids research, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Characterizing and measuring bias in sequence data.Genome biology · 2013Article
- Effort required to finish shotgun-generated genome sequences differs significantly among vertebrates.BMC genomics · 2010Article
- Global repeat discovery and estimation of genomic copy number in a large, complex genome using a high-throughput 454 sequence survey.BMC genomics · 2007Article
- An intermediate grade of finished genomic sequence suitable for comparative analyses.Genome research · 2004Article
- An efficient strategy for large-scale high-throughput transposon-mediated sequencing of cDNA clones.Nucleic acids research · 2002Article
- Systematic sequencing of cDNA clones using the transposon Tn5.Nucleic acids research · 2002Article
- High-throughput plasmid purification for capillary sequencing.Genome research · 2001Article
- Functional genomics in Caenorhabditis elegans: An approach involving comparisons of sequences from related nematodes.Genome research · 1999Article
- Analysis of the quality and utility of random shotgun sequencing at low redundancies.Genome research · 1998Article
- From amplification to gene in thyroid cancer: a high-resolution mapped bacterial-artificial-chromosome resource for cancer chromosome aberrations guides gene discovery after comparative genome hybridization.American journal of human genetics · 1998Article
- Sequencing multimegabase-template DNA with BigDye terminator chemistry.Genome research · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Representation of subcloned Caenorhabditis elegans and human DNA sequences in both M13 and pUC sequencing vectors was determined in the context of large scale genomic sequencing. In many cases, regions of subclone under-representation correlated with the occurrence of repeat sequences, and in some cases the under-representation was orientation specific. Factors which affected subclone representation included the nature and complexity of the repeat sequence, as well as the length of the repeat region. In some but not all cases, notable differences between the M13 and pUC subclone distributions existed. However, in all regions lacking one type of subclone (either M13 or pUC), an alternate subclone was identified in at least one orientation. This suggests that complementary use of M13 and pUC subclones would provide the most comprehensive subclone coverage of a given genomic sequence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.