ArticleProceedings of the National Academy of Sciences of the United States of America1997
Nonexponential kinetics of a single tRNAPhe molecule under physiological conditions.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 115 citations in OpenAlex.
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- Dynamics and folding of single two-stranded coiled-coil peptides studied by fluorescent energy transfer confocal microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- Free Brownian motion of individual lipid molecules in biomembranes.Biophysical journal · 1999Article
- The dynamics of structural deformations of immobilized single light-harvesting complexes.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Monitoring conformational dynamics of a single molecule by selective fluorescence spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Fluorescence and photobleaching dynamics of single light-harvesting complexes.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The fluorescence decay functions of individual, specifically labeled tRNAPhe molecules exhibit nonexponential character as a result of conformational dynamics occurring during the measurement on a single molecule. tRNAPhe conformational states that interchange much more slowly are evidenced by the distribution of lifetimes observed for many individual molecules. A structural model for the nonexponential decay indicates that the tRNAPhe-probe adduct fluctuates between two states, one of which provides conditions that quench the probe fluorescence.
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