ReviewImmunologic research1997
C-reactive protein: structural biology, gene expression, and host defense function.
Review in Immunologic research, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Targeting C-Reactive Protein by Selective Apheresis in Humans: Pros and Cons.Journal of clinical medicine · 2022Review
- An overview onHeliyon · 2020Review
- Phase Variation ofMicrobiology spectrum · 2019Article
- Postprandial lipemic and inflammatory responses to high-fat meals: a review of the roles of acute and chronic exercise.Nutrition & metabolism · 2016Review
- Possible potentiation by certain antioxidants of the anti-inflammatory effects of diclofenac in rats.TheScientificWorldJournal · 2014Article
- C-reactive protein in human atherogenesis: facts and fiction.Mediators of inflammation · 2014Review
- Interleukin-6 (IL-6) and C-reactive protein (CRP) concentration prior to total nephrectomy are prognostic factors in localized renal cell carcinoma (RCC).Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2013Article
- CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?Journal of translational medicine · 2009Review
- Complexity of complement activation in sepsis.Journal of cellular and molecular medicine · 2008Review
- Racial differences in C-reactive protein levels during normal pregnancy.American journal of obstetrics and gynecology · 2008Article
- Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (Fc gamma RI)-dependent.The American journal of pathology · 2008Article
- Mannose-binding lectin does not act as an acute-phase reactant in adults with community-acquired pneumococcal pneumonia.Clinical and experimental immunology · 2006Article
- Carbohydrate ligands of human C-reactive protein: binding of neoglycoproteins containing galactose-6-phosphate and galactose-terminated disaccharide.Glycoconjugate journal · 2006Article
- Mannose binding lectin acute phase activity in patients with severe infection.Journal of clinical immunology · 2005Article
- Macrophage conditioned medium induces the expression of C-reactive protein in human aortic endothelial cells: potential for paracrine/autocrine effects.The American journal of pathology · 2005Article
- Direct modulatory effect of C-reactive protein on primary human monocyte adhesion to human endothelial cells.Clinical and experimental immunology · 2002Article
- Effects of C-reactive protein and pentosan polysulphate on human complement activation.Immunology · 2002Article
- Varied biologic functions of C-reactive protein: lessons learned from transgenic mice.Immunologic research · 2002Review
- Diversity and duplicity: human FCgamma receptors in host defense and autoimmunity.Immunologic research · 2002Review
- Expression of C-reactive protein in the human respiratory tract.Infection and immunity · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past few years substantial insight was gained into the biology and biochemistry of human C-reactive protein (CRP). X-ray crystallography in conjunction with mutational analyses, generated the three-dimensional structure of the protein and indicated the topology and structure of ligand-binding sites. Using human CRP transgenic mice infected with Streptococcus pneumoniae, we obtained data that clearly established CRP as an important host defense molecule. Studies using the same mice revealed a previously unknown testosterone-dependence of constitutive expression of human CRP. In this article we provide a brief overview of these recent findings.
Indexed as
Identifiers
9212359What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.